product summary
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company name :
MyBioSource
product type :
antibody
product name :
Collagen Type II antibody
catalog :
MBS530216
quantity :
0.1 mg
price :
615 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6B3
reactivity :
human, mouse, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530216
products type :
Antibody
products full name :
Collagen Type II antibody
products short name :
Collagen Type II
products name syn :
Monoclonal Collagen Type II; Anti-Collagen Type II; Chondrocalcin; COL11A3; Cartilage collagen; COL2A1
other names :
Collagen, type II, alpha 1; Collagen alpha-1(II) chain; collagen alpha-1(II) chain; collagen, type II, alpha 1; Alpha-1 type II collagen
other gene names :
COL2A1; COL2A1; AOM; ANFH; SEDC; STL1; COL11A3
uniprot entry name :
CO2A1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
6B3
host :
Mouse
reactivity :
Chicken, Human, Mouse, Salamander
sequence length :
1487
purity :
Collagen Type II antibody was purified by Protein G chromatography.
form :
Antibody purified from Ascites fluid by Protein G Chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
concentration :
0.2 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB)
app notes :
IHC-F: 1-2 ug/ml. IHC-P: 1-2 ug/ml
other info1 :
Biological Significance: Collagen is a group of naturally occurring proteins. In nature, it is found exclusively in animals, especially in the flesh and connective tissues of mammals. Type-II collagen is the basis for articular cartilage and hyaline cartilage. It makes up 50% of all protein in cartilage and 85-90% of collagen of articular cartilage. Type II collagen does form fibers. This fibrillar network of collagen allows cartilage to entrap the proteoglycan aggregate as well as provide tensile strength to the tissue.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: Collagen type II antibody was raised in mouse using purified type II collagen as the immunogen.
products categories :
Cancer
products description :
Mouse monoclonal Collagen Type II antibody
ncbi gi num :
95132445
ncbi acc num :
AAI16450.1
uniprot acc num :
P02458
ncbi mol weight :
29,781 Da
ncbi pathways :
Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway 730306!!Collagen Biosynthesis And Modifying Enzymes Pathway 645289!!Collagen Formation Pathway 645288!!ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479!!Endochondral Ossification Pathway 198812!!Extracellular Matrix Organization Pathway 576262!!Focal Adhesion Pathway 198795
ncbi summary :
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
615 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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