product summary
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company name :
MyBioSource
product type :
antibody
product name :
Drebrin antibody
catalog :
MBS530211
quantity :
0.1 mg
price :
665 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M2F6
reactivity :
human, mouse, rat, cow
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530211
products type :
Antibody
products full name :
Drebrin antibody
products short name :
Drebrin
products name syn :
Monoclonal Drebrin; Anti-Drebrin
other names :
drebrin isoform a; Drebrin; drebrin; drebrin 1; Developmentally-regulated brain protein
other gene names :
DBN1; DBN1; D0S117E; D0S117E
uniprot entry name :
DREB_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
M2F6
host :
Mouse
reactivity :
Bovine, Cat, Human, Mouse, Rabbit, Rat
sequence length :
649
specificity :
Chicken
form :
PBS with 50% glycerol, pH 7.2.
concentration :
1.0 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Immunohistochemistry (IHC), Western Blot (WB)
app notes :
IHC: 10 ug/ml. WB: 5-10 ug/ml
other info1 :
Biological Significance: Drebrins (developmentally regulated brain proteins) are thought to be active in regulating the development and differentiation of neuronal tissue because they are expressed peculiarly in the course of development of neuronal tissues. Drebrin proteins are classified into an embryonic form (E) and an adult form (A) in mammals. The embryonic form is further classified into E1 and E2 in the chicken.
other info2 :
Immunogen: Drebrin antibody was raised in mouse using purified chicken drebrin E as the immunogen.
products categories :
Neuroscience
products description :
Mouse monoclonal Drebrin antibody
ncbi gi num :
18426915
ncbi acc num :
NP_004386.2
ncbi gb acc num :
NM_004395.3
uniprot acc num :
Q16643
ncbi mol weight :
76,300 Da
ncbi summary :
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
DBN1: a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer s disease. Expressed in brain neurons, heart, placenta, skeletal muscle, kidney and pancreas. Two alternatively spliced isoforms have been described. Protein type: Cytoskeletal; Motility/polarity/chemotaxis; Actin-binding. Chromosomal Location of Human Ortholog: 5q35.3. Cellular Component: cytoplasm; dendrite; gap junction; plasma membrane; actomyosin; cell cortex; actin cytoskeleton. Molecular Function: protein binding; actin binding; profilin binding. Biological Process: maintenance of cellular protein localization; regulation of dendrite development; actin filament organization; regulation of neuronal synaptic plasticity
size1 :
0.1 mg
price1 :
665 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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