catalog number :
MBS5302103
products full name :
TSH beta antibody
products short name :
[TSH beta]
products name syn :
[Polyclonal TSH Beta antibody, Anti-TSH Beta antibody, Thyroid stimulating hormone beta subunit antibody, TSHB antibody, Thyroid stimulating hormone beta precursor antibody, Thyrotropin beta chain precursor antibody, Thyrotropin beta subunit antibody, CHNG4 antibody]
other names :
[thyrotropin subunit beta; Thyrotropin subunit beta; thyrotropin subunit beta; thyroid stimulating hormone, beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain]
products gene name :
[TSH beta]
other gene names :
[Tshb; Tshb; TSH-B; TSH-beta]
uniprot entry name :
TSHB_RAT
reactivity :
The antibody was absorbed against solid phase HCG to remove activity to the a subunit.
specificity :
TSH beta antibody was raised against Human TSH (intact).
form :
Clear 0.2 um filtered liquid in 10 mM Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.05% Sodium Azide.
concentration :
6.68 mg/ml
tested application :
Suitable for use in most immunoassay formats. Optimal working dilutiomns should be determined by investigator.
app notes :
The optimal working dilution should be determined by the end user
other info1 :
Host Note: Goat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian. Biological Significance: Thyroid-stimulating hormone is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid gland. The beta subunit is unique to TSH, and therefore determines its receptor specificity.
other info2 :
Immunogen: TSH from human pituitary glands.
products categories :
Hormones & Steroids; Purified Polyclonal Antibodies
products description :
Affinity purified Goat polyclonal TSH beta antibody
ncbi acc num :
NP_037248.2
ncbi gb acc num :
NM_013116.2
ncbi pathways :
Amine-derived Hormones Pathway (1178245); Autoimmune Thyroid Disease Pathway (83509); Autoimmune Thyroid Disease Pathway (533); Class A/1 (Rhodopsin-like Receptors) Pathway (1177697); G Alpha (s) Signalling Events Pathway (1177727); GPCR Downstream Signaling Pathway (1177726); GPCR Ligand Binding Pathway (1177696); Glycoprotein Hormones Pathway (1177203); Hormone Ligand-binding Receptors Pathway (1177711); Metabolism Pathway (1178040)
ncbi summary :
mutation of the human homolog is a rare cause of hereditary hypothyrodism [RGD, Feb 2006]
uniprot summary :
Indispensable for the control of thyroid structure and metabolism.