product summary
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company name :
MyBioSource
product type :
antibody
product name :
Vinculin antibody
catalog :
MBS530170
quantity :
0.1 mg
price :
395 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
V284
reactivity :
human, mouse, rat, chicken
application :
western blot, immunohistochemistry, immunoprecipitation
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530170
products type :
Antibody
products full name :
Vinculin antibody
products short name :
Vinculin
products name syn :
Monoclonal Vinculin; Anti-Vinculin
other names :
vinculin, partial; Vinculin; vinculin; vinculin; Metavinculin; MV
other gene names :
VCL; VCL; MV; MVCL; CMD1W; CMH15; HEL114; MV
uniprot entry name :
VINC_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
V284
host :
Mouse
reactivity :
Chicken, Mouse, Rabbit, Rat
sequence length :
56
specificity :
Human
purity :
Vinculin antibody was purified by Protein A chromatography.
form :
Protein A purified IgG1 supplied in PBS, pH 7.4, with 1mg/ml BSA and 0.05% NaN3.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
tested application :
Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
other info1 :
Biological Significance: In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is associated with focal adhesion and adherens junctions, which are complexes that nucleates actin filaments and crosslinkers between the external medium, plasma membrane, and actin cytoskeleton.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: Vinculin antibody was raised in mouse using human vinculin as the immunogen.
products categories :
Cell Biology
products description :
Mouse monoclonal Vinculin antibody
ncbi gi num :
292902
ncbi acc num :
AAA61271.1
uniprot acc num :
P18206
ncbi mol weight :
117 kDa (predicted detection band MW)
ncbi pathways :
Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Bacterial Invasion Of Epithelial Cells Pathway 149807!!Bacterial Invasion Of Epithelial Cells Pathway 148661!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!Hemostasis Pathway 106028
ncbi summary :
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
395 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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