product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
ACE antibody
catalog :
MBS530166
quantity :
0.1 ml
price :
745 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2.00E+02
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530166
products type :
Antibody
products full name :
ACE antibody
products short name :
ACE
products name syn :
Monoclonal ACE; Anti-ACE; Angiotensin Converting Enzyme; CD143
other names :
Angiotensin-converting enzyme; Angiotensin-converting enzyme; angiotensin-converting enzyme; angiotensin I converting enzyme; Dipeptidyl carboxypeptidase I; Kininase II; CD_antigen: CD143
products gene name :
ACE
other gene names :
ACE; ACE; DCP; ICH; ACE1; DCP1; CD143; MVCD3; DCP; DCP1; ACE
uniprot entry name :
ACE_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2.00E+02
host :
Mouse
reactivity :
Bovine, Dog, Cat, Guinea Pig, Monkey, Rabbit, Rat, Mouse
sequence length :
1306
specificity :
Human
form :
PBS, pH 7.4, with 150 mM NaCl.
concentration :
1.0 mg/ml
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
tested application :
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
app notes :
IHC-P: 5-10 ug/ml, WB: 5 ug/ml
other info1 :
Biological Significance: Angiotensin I-converting enzyme an exopeptidase, is a circulating enzyme that participates in the body's renin-angiotensin system (RAS), which mediates extracellular volume (i.e. that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. It is secreted by pulmonary and renal endothelial cells and catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II.
other info2 :
Immunogen: ACE antibody was raised in mouse using ACE (denatured) from human kidney as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Mouse monoclonal ACE antibody
ncbi gi num :
113045
ncbi acc num :
P12821.1
uniprot acc num :
P12821
ncbi mol weight :
78,694 Da
ncbi pathways :
ACE Inhibitor Pathway 198763!!Chagas Disease (American Trypanosomiasis) Pathway 147809!!Chagas Disease (American Trypanosomiasis) Pathway 147795!!Hypertrophic Cardiomyopathy (HCM) Pathway 114229!!Hypertrophic Cardiomyopathy (HCM) Pathway 106591!!Metabolism Of Angiotensinogen To Angiotensins Pathway 685555!!Metabolism Of Proteins Pathway 106230!!Peptide Hormone Metabolism Pathway 771603!!Renin-angiotensin System Pathway 83075!!Renin-angiotensin System Pathway 486
ncbi summary :
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
size :
0.1 ml
price :
745 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!