This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MUC1 antibody
catalog :
MBS530071
quantity :
1 ml
price :
650 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MA552
reactivity :
human
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
catalog number :
MBS530071
products type :
Antibody
products full name :
MUC1 antibody
products short name :
MUC1
products name syn :
Monoclonal MUC1; Anti-MUC1; MU 1c; Mucin-1; MUC1; MU-1c
other names :
MUC1; Mucin-1; mucin-1; mucin 1, cell surface associated; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3
products gene name :
MUC1
other gene names :
MUC1; MUC1; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; PUM; MUC-1; CA 15-3; KL-6; PUM; PEM; EMA; MUC1-NT; MUC1-alpha; MUC1-beta
uniprot entry name :
MUC1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
MA552
host :
Mouse
reactivity :
To be determined by end-user
sequence length :
255
specificity :
Human
form :
Lyophilized from PBS, pH7.6, with 1% BSA and 15mM NaN3. Reconstitute with 1 ml of distilled water.
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC) Paraffin
app notes :
IHC-P: 1:100
other info1 :
Biological Significance: Mucins are heavily glycosylated proteins which constitute the major components of mucus covering the surface of epithelial tissues. Nine distinct epithelial mucin genes (Muc-1, 2, 3, 4, 5AC, 5B, 6, 7 and 8) have been identified. Various immunohistochemical and in situ hybridization studies have reported that these mucins are differentially expressed in epithelia with cell-type specificity. In gastric cancer, alterations in mucin polypeptide expression have been reported, including the loss of expression of Muc-5AC glycoprotein, increased mucin heterogeneity, glycosylation changes and the expression of simple mucin-type carbohydrates.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: MUC1 antibody was raised in mouse using human breast cancer cell line ZR75-1 as the immunogen.
products categories :
Immunology
products description :
Mouse monoclonal MUC1 antibody
ncbi gi num :
541680
ncbi acc num :
CAA56734.1
uniprot acc num :
P15941
ncbi mol weight :
28,297 Da
ncbi pathways :
IL-7 Signaling Pathway 198857!!Metabolism Of Proteins Pathway 106230!!O-linked Glycosylation Pathway 1127679!!O-linked Glycosylation Of Mucins Pathway 530747!!Post-translational Protein Modification Pathway 161012!!Termination Of O-glycan Biosynthesis Pathway 530748
ncbi summary :
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
size :
1 ml
price :
650 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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