This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
CD74 antibody
catalog :
MBS530012
quantity :
0.1 mg
price :
460 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M-B741
reactivity :
human
application :
flow cytometry, FACS
product information
catalog number :
MBS530012
products type :
Antibody
products full name :
CD74 antibody
products short name :
CD74
products name syn :
Monoclonal CD74; Anti-CD74; CD 74; CD74; CD-74
other names :
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated), isoform CRA_c; HLA class II histocompatibility antigen gamma chain; HLA class II histocompatibility antigen gamma chain; CD74 molecule, major histocompatibility complex, class II invariant chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD_antigen: CD74
products gene name :
CD74
other gene names :
CD74; CD74; II; DHLAG; HLADG; Ia-GAMMA; DHLAG; Ii
uniprot entry name :
HG2A_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
M-B741
host :
Mouse
reactivity :
To be determined by end-user
sequence length :
296
specificity :
Human
purity :
> 95% pure. CD74 antibody was purified by Protein A chromatography.
form :
50mM Na3PO4, pH 7.5, with 100mM KCL, 150mM NaCl, and 0.5 mg/ml gentamycin sulfate.
concentration :
1.0 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Flow Cytometry (FC/FACS)
app notes :
FC: 5 ug/ml
other info1 :
Biological Significance: Human CD74 is expressed intracellularly and on the cell surface of MHC Class II positive cells such as B cells, monocytes, macrophages, Langerhans cells and dendritic cells. CD74 has several important functions relating to antigen presentation by MHC Class II molecules.
other info2 :
Immunogen: CD74 antibody was raised in mouse using RPMI 1788 Cell line as the immunogen.
products categories :
Immunology
products description :
Mouse monoclonal CD74 antibody
products references :
6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors; Jiaqiang Caia, Mark Baugha, Darcey Blacka, Clive Longa, D. Jonathan Bennetta, Maureen Dempstera, Xavier Fraderaa, Jonathan Gillespiea, Fiona Andrewsa, Sylviane Boucharensa, John Bruina, Kenneth S. Camerona, Iain Cumminga, William Hamiltona, Philip S. Jonesa, Allard Kapteinb, Emma Kinghorna, Maurice Maidmenta, Iain Martina, Ann Mitchella, Zoran Rankovica, John Robinsona, Paul Sculliona, Joost C.M. Uitdehaagb, Paul Vinkb, Paul Westwooda, Mario van Zeelandb, Leon van Berkomc, Martijn Bastianic, Tommi Meulemansc (Bioorganic & Medicinal Chemistry Letters: Volume: 20 Issue: 15 Page: 4350-4354 DOI: 10.1016/j.bmcl.2010.06.072)
ncbi gi num :
119582135
ncbi acc num :
EAW61731.1
uniprot acc num :
P04233
ncbi mol weight :
18,328 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Antigen Processing And Presentation Pathway 83074!!Antigen Processing And Presentation Pathway 485!!Herpes Simplex Infection Pathway 377873!!Herpes Simplex Infection Pathway 377865!!Immune System Pathway 106386!!MHC Class II Antigen Presentation Pathway 645290!!Tuberculosis Pathway 213780!!Tuberculosis Pathway 213743
ncbi summary :
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
size :
0.1 mg
price :
460 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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