catalog number :
MBS520528
products full name :
Anti-Mouse CD157 (CD157), FITC, (clone KT157), (Rat IgG2c)
products short name :
CD157 (CD157)
products name syn :
CD157 (CD157), FITC, (clone KT157), (Rat IgG2c); Purified Anti-Mouse CD157 Receptor Monoclonal Antibody
other names :
CD157 protein; CD157 protein
products gene name :
CD157 (CD157)
specificity :
CD157 (Mouse CD157)
concentration :
0.1 mg/ml
storage stability :
For all formats, store at 4 degree C. For long term storage (Ascites, Purified, Biotin, FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
other info1 :
Immunogen: T cell hybridoma J774. Donor: Balb/c mouse spleen cells. Fusion Partner: NSO Mouse Myeloma Partner
other info2 :
Presentation: Biotin/FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
products description :
anti-mouse CD157 monoclonal antibody detects the mouse CD157 receptor. CD157 also known as BP-3 Alloantigen or Bone marrow STromal cell antigen-1 (BST-1), is a 38-48 KDa differentially glycosylated glycosylphosphatidylinositol (GPI) anchored cell surface glycoprotein. CD157, like CD38 belongs to a family of genetically related pleiotropic ectoenzymes. The CD157 antigen is expressed on thymocytes, bone marrow B cells, neutrophils, macrophages, stromal cells, intestinal epithelial cells, the collecting tubules of the kidney and reticular cells in lymph nodes. The CD157 receptor has ADP ribosyl cyclase and cyclic ADP ribose hydrolase biochemical activities. Studies show CD157 is a receptor that induces reorganization of the cytoskeleton and significant changes in cell shape. CD157 is also a mediator of neutrophil adhesion and migration. Signals mediated by CD157 act through modulation of cytosolic [Ca2+]. CD157 is also involved in cellular adhesion to the extracellular matrix. This anti-body has been reported to work in Flow Cytometry.
ncbi acc num :
NP_001267575.1
ncbi gb acc num :
NM_001280646.1