product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-Mouse CD19 Antigen Monoclonal Antibody
catalog :
MBS520486
quantity :
0.05 mg
price :
225 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
6D5
reactivity :
human, mouse
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS520486
products type :
Antibody
products full name :
Anti-Mouse CD19 Antigen Monoclonal Antibody
products short name :
CD19
products name syn :
CD19, PE (Clone 6D5) (rat IgG2a); PE Anti-Mouse CD19 Monoclonal Antibody
other names :
CD19; B-lymphocyte antigen CD19; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4; CD19 molecule; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12
products gene name :
CD19
other gene names :
CD19; CD19; B4; CVID3
uniprot entry name :
CD19_HUMAN
clonality :
Monoclonal
isotype :
Rat IgG2a
clone :
6D5
host :
Rat
reactivity :
Mouse
sequence length :
556
specificity :
Mouse CD19
form :
PE
concentration :
Antibody Concentration: 0.1 mg/ml
storage stability :
For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Purified, FITC) aliquot and freeze unused portion at -20 Degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
other info2 :
Presentation: FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
products description :
anti-mouse CD19 antigen monoclonal antibody is a pan B cell marker. It will not detect plasma cells. This antibody is suitable for use in flow cytometry.
ncbi gi num :
901823
ncbi acc num :
AAA69966.1
uniprot acc num :
P15391
ncbi mol weight :
61,128 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Antigen Activates B Cell Receptor Leading To Generation Of Second Messengers Pathway (576249); B Cell Receptor Signaling Pathway (198909); B Cell Receptor Signaling Pathway (83081); B Cell Receptor Signaling Pathway (492); BCR Signaling Pathway (138058); Constitutive PI3K/AKT Signaling In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764)
ncbi summary :
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Subunit structure: Forms a complex with CD21, CD81 and CD225 in the membrane of mature B-cells. Interacts with VAV. Interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. Interacts with PLCG2 when phosphorylated on Tyr-409. Interacts with LYN. Ref.11 Ref.13. Subcellular location: Membrane; Single-pass type I membrane protein. Post-translational modification: Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation. Phosphorylated on tyrosine residues by LYN. Ref.11 Ref.12 Ref.13. Involvement in disease: Immunodeficiency, common variable, 3 (CVID3) [MIM:613493]: A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.14. Sequence similarities: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Sequence caution: The sequence AAA35533.1 differs from that shown. Reason: Frameshift at position 396.
size1 :
0.05 mg
price1 :
225 USD
size2 :
0.3 mg
price2 :
470
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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