catalog number :
MBS520090
products full name :
Anti-Rat CD28 Biotin (Clone JJ319) (mouse IgG1)
products short name :
CD28
products name syn :
CD28 Biotin (Clone JJ319) (mouse IgG1); Biotin Anti-Rat CD28 Monoclonal Antibody
other names :
T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28
products gene name :
CD28
other gene names :
CD28; CD28
uniprot entry name :
CD28_RABIT
specificity :
CD28 (Tp44; receptor for B7 family) (Rat CD28)
form :
Biotin (Biotin conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from Bioreactor supernatant via Protein G Chromatography))
concentration :
Antibody Concentration: 0.1 mg/ml
storage stability :
Store at 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Rat CD28 transfected A20J cells. Donor: BALB/c spleen. Fusion Partner: X63-Ag 8.653
other info2 :
Presentation: 100 ug or 500 ug Biotin conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
products description :
anti-rat CD28 monoclonal antibody recognizes a 90kDa homeodimeric cell surface glycoprotein. CD28 has been found to be a potent costimulatory receptor on T cells. It is expressed on all peripheral rat ab and most gd T cells, as well as on approximately half of all NK cells. This clone can costimulate T cell proliferation and IL-2 secretion by resting rat T cells. Applications: Flow cytometry
ncbi acc num :
NP_001075676.1
ncbi gb acc num :
NM_001082207.1
ncbi mol weight :
25,307 Da
uniprot summary :
Function: Possibly involved in T-cell activation . By similarity. Subunit structure: Homodimer; disulfide-linked. Interacts with DUSP14. Binds to CD80/B7-1 and CD86/B7-2/B70 . By similarity. Subcellular location: Membrane; Single-pass type I membrane protein. Sequence similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.