product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-Mouse CD200, Purified (Clone OX90) (rat IgG2a)
catalog :
MBS520069
quantity :
0.25 mg
price :
280 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
OX90
reactivity :
human, mouse
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS520069
products type :
Antibody
products full name :
Anti-Mouse CD200, Purified (Clone OX90) (rat IgG2a)
products short name :
CD200
products name syn :
CD200, Purified (Clone OX90) (rat IgG2a); Anti-Mouse CD200 (OX2) Monoclonal Antibody
other names :
CD200 antigen, isoform CRA_a; OX-2 membrane glycoprotein; OX-2 membrane glycoprotein; CD200 antigen; MRC OX-2 antigen; antigen identified by monoclonal antibody MRC OX-2; CD200 molecule
products gene name :
CD200
other gene names :
CD200; CD200; MRC; MOX1; MOX2; OX-2; MOX1; MOX2
uniprot entry name :
OX2G_HUMAN
clonality :
Monoclonal
isotype :
Rat IGg2a
clone :
OX90
host :
Rat
reactivity :
Mouse
sequence length :
269
specificity :
CD200 (Mouse CD200 (OX2))
form :
Purified
concentration :
Antibody Concentration: 0.1 mg/ml
storage stability :
For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Purified, Biotin and FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC), ELISA (EIA)
other info1 :
Immunogen: mouse CD200-rat CD4 fusion protein. Donor: Rat spleen. Fusion Partner: Y3 myeloma
other info2 :
Presentation: Purified IgG buffered in PBS and 0.02% NaN3. (Purified from ascitic fluid via Protein G Chromatography). For maximum recovery of contents, spin down tube before use.
products description :
anti-mouse CD200 monoclonal antibody reacts with CD200 (OX2), a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, and brain tissue (neurons). CD200 consists of 2 immunoglobulin (Ig) domains, a Cterminus transmembrane domain and a small cytoplasmic domain (19 aa) which lacks signaling motifs. CD200 is the ligand for CD200 receptor (CD200R), which is very similar in structure to CD200 except that it has a larger cytoplasmic domain (67 aa), and its expression is restricted to myeloid-derived antigen presenting cells (APC's) and certain populations of T cells. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation. This clone is suitable for use in flow cytometry, immunohistochemistry (frozen sections) and ELISA.
ncbi gi num :
119600082
ncbi acc num :
EAW79676.1
uniprot acc num :
P41217
ncbi mol weight :
31,264 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413)
ncbi summary :
The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. Subunit structure: Interacts with CD200R1. Subcellular location: Cell membrane; Single-pass type I membrane protein. Sequence similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.
size1 :
0.25 mg
price1 :
280 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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