product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-Rat CD152 Biotin (Clone WKH 203) (mouse IgG1)
catalog :
MBS520057
quantity :
0.1 mg
price :
250 USD
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
[WKH 203]
application :
immunohistochemistry
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS520057 image 1
product information
catalog number :
MBS520057
products type :
Antibody
products full name :
Anti-Rat CD152 Biotin (Clone WKH 203) (mouse IgG1)
products short name :
[CD152]
products name syn :
[CD152 Biotin (Clone WKH 203) (mouse IgG1); Biotin Anti-Rat CD152 (CTLA-4) Monoclonal Antibody]
products gene name :
[CD152]
clonality :
Monoclonal
isotype :
mouse IgG1
clone :
[WKH 203]
host :
Mouse
reactivity :
Rat
specificity :
Rat CD152
form :
Biotin
concentration :
0.1 mg/ml
storage stability :
Store at 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC)
image1 heading :
Testing Data
other info1 :
Immunogen: Purified rCTLA-4hlg fusion protein. Donor: BALB/c mice spleen cells. Fusion Partner: X63 Ag8.653 myeloma cells
other info2 :
Presentation: Biotin conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
products description :
anti-rat CD152 monoclonal antibody is specific for the cytotoxic T lymphocyte-associated protein 4 (CTLA-4), also called CD152. This antigen is known to be the receptor for B7 ligands (CD80 and CD86) present on antigen presenting cells. A subset of CD4 T cells expressing CD25 and CTLA-4 has been recognized as a potent suppressor cell population, counteracting autoimmunity and inflammation. These 'regulatory' T cells (Treg) which produce the anti-inflammatory cytokine interleukin-10 (IL-10) but not IL-2, are able to suppress the proliferation of costimulated CD25- negative indicator cells. The capacity of these naturally occurring regulatory T cells to suppress autoimmunity and inflammation suggests that therapies which activate and expand this subset could become extremely effective treatments for these immunopathological disorders. This clone has been tested in flow cytometry. In rats, the constitutive expression of CTLA-4 at the level detectable by flow cytometry is restricted to the CD25+ subset of CD4 T cells and thymocytes.
size1 :
0.1 mg
price1 :
250 USD
size2 :
0.5 mg
price2 :
420
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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