This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Anti-Rat CD134, Purified (Clone OX40) (mouse IgG2b)
catalog :
MBS520049
quantity :
0.25 mg
price :
250 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OX40
reactivity :
human, rat
application :
immunohistochemistry, flow cytometry, FACS
product information
catalog number :
MBS520049
products type :
Antibody
products full name :
Anti-Rat CD134, Purified (Clone OX40) (mouse IgG2b)
products short name :
CD134
products name syn :
CD134, Purified (Clone OX40) (mouse IgG2b); Anti-Rat CD134 (OX40) Monoclonal Antibody
other names :
CD134 antigen; Tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily member 4; OX40 antigen; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 homologue; OX40L receptor; OX40 cell surface antigen; lymphoid activation antigene ACT35; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1 receptor; tumor necrosis factor receptor superfamily, member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor
products gene name :
CD134
other gene names :
TNFRSF4; TNFRSF4; OX40; ACT35; CD134; TXGP1L; TXGP1L
uniprot entry name :
TNR4_HUMAN
clonality :
Monoclonal
isotype :
Mouse IgG2b
clone :
OX40
host :
Mouse
reactivity :
Rat
sequence length :
277
specificity :
CD134 (Rat CD134 (OX40))
purity :
Purified Ig buffered in PBS and 0.02% NaN3. (Purified from ascites fluid via Protein G Chromatography).
form :
Purified
concentration :
1.0 mg/ml
storage stability :
For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Purified, Biotin, FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
other info1 :
Immunogen: Phytohaemagglutinin-activated rat lymph node cells. Donor: Mouse spleen. Fusion Partner: NS1/1.Ag4.1 cell line
other info2 :
Presentation: Purified IgG buffered in PBS and 0.02% NaN3. (Purified from ascitic fluid via Protein G Chromatography).
products description :
anti-rat CD134 (OX40) monoclonal antibody recognizes an antigen related to NGF on activated T cells that also express CD4. It detects a single chain of 51-55 kDa (unreduced) and 47-51 kDa (reduced) in immunoprecipitation assay1. OX40/OX40L interaction has been shown to deliver a potent costimulatory signal to the CD4+ T cell4. While mouse OX40 shows 90% homology with rat, it is expressed on both CD4+ and CD8+ cells in the mouse. This antibody was shown to block binding of OX40L to OX403. This antibody is suitable for use in flow cytometry and immunohistochemistry (frozen sections). It has also been reported as suitable for use in protein purification5.
ncbi gi num :
8926702
ncbi acc num :
CAB96543.1
uniprot acc num :
P43489
ncbi mol weight :
29,341 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Downstream Signaling In Naive CD8+ T Cells Pathway 138018
ncbi summary :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Receptor for TNFSF4/OX40L/GP34. Subunit structure: Interacts with TRAF2, TRAF3 and TRAF5. Ref.7 Ref.8. Subcellular location: Membrane; Single-pass type I membrane protein. Sequence similarities: Contains 4 TNFR-Cys repeats. Sequence caution: The sequence AAB33944.1 differs from that shown. Reason: Erroneous initiation.
size :
0.25 mg
price :
250 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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