This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Anti-Mouse CD134, FITC (Clone OX-86) (rat IgG1)
catalog :
MBS520047
quantity :
0.1 mg
price :
220 USD
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
OX-86
reactivity :
human, mouse
application :
immunohistochemistry
product information
catalog number :
MBS520047
products type :
Antibody
products full name :
Anti-Mouse CD134, FITC (Clone OX-86) (rat IgG1)
products short name :
CD134
products name syn :
CD134, FITC (Clone OX-86) (rat IgG1); Anti-Mouse CD134 (OX-40 antigen) Monoclonal Antibody
other names :
CD134 antigen; Tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily member 4; OX40 antigen; ACT35 antigen; ATC35 antigen; CD134 antigen; OX40 homologue; OX40L receptor; OX40 cell surface antigen; lymphoid activation antigene ACT35; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1 receptor; tumor necrosis factor receptor superfamily, member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor
products gene name :
CD134
other gene names :
TNFRSF4; TNFRSF4; OX40; ACT35; CD134; TXGP1L; TXGP1L
uniprot entry name :
TNR4_HUMAN
clonality :
Monoclonal
isotype :
Rat IGg1
clone :
OX-86
host :
Rat
reactivity :
Mouse
sequence length :
277
specificity :
CD134 (OX-40 Antigen) (Mouse CD134 (OX-40 antigen))
form :
FITC
concentration :
0.1 mg/ml
storage stability :
For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Purified, Biotin and FITC), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant mouse OX-40 antigen. Donor: Rat AO spleen. Fusion Partner: NS1
other info2 :
Presentation: Biotin/FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
products description :
PE anti-mouse CD134 monoclonal antibody detects the mouse OX-40 antigen (CD134) which is a member of the tumor necrosis factor (TNF) receptor/nerve growth factor (NGF) receptor superfamily. The OX-40 antigen is the sole receptor for the OX-40 ligand. This antibody (clone OX-86) labels the OX-40 antigen found on both mouse CD4 and CD8 single positive activated T cells. This is in contrast to rat OX-40 which is only found on CD4 positive T blasts (not CD8). Also, the OX-86 mAb does not block binding of the OX-40L. This antibody is suitable for use in flow cytometry.
ncbi gi num :
8926702
ncbi acc num :
CAB96543.1
uniprot acc num :
P43489
ncbi mol weight :
29,341 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Downstream Signaling In Naive CD8+ T Cells Pathway 138018
ncbi summary :
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Receptor for TNFSF4/OX40L/GP34. Subunit structure: Interacts with TRAF2, TRAF3 and TRAF5. Ref.7 Ref.8. Subcellular location: Membrane; Single-pass type I membrane protein. Sequence similarities: Contains 4 TNFR-Cys repeats. Sequence caution: The sequence AAB33944.1 differs from that shown. Reason: Erroneous initiation.
size :
0.1 mg
price :
220 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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