catalog number :
MBS520037
products full name :
Anti-Mouse CD11b, Biotin (Clone M1/70.15) (rat IgG2b)
products short name :
CD11b
products name syn :
CD11b, Biotin (Clone M1/70.15) (rat IgG2b); Biotin Anti-Mouse CD11b Monoclonal Antibody
other names :
CD11b; integrin alpha-M
products gene name :
CD11b
other gene names :
ITGAM; CD11B
specificity :
CD11b (Mac-1; Ly 40; CR3a) (Mouse CD11b (MAC-1, Ly-40))
form :
Biotin (Biotin conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. (Purified from ascitic fluid via Protein G Chromatography))
concentration :
Antibody Concentration: 0.1 mg/ml
storage stability :
Store at 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
other info1 :
Immunogen: C57BL/10 spleen cell enriched for T lymphocytes. Donor: DA rat spleen. Fusion Partner: NS-1
other info2 :
Presentation: 100 ug or 300 ug Biotin conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
products description :
anti-mouse CD11b (Mac-1; Ly 40) monoclonal antibody is specific for the 170 kDa a subunit of Mac-1 which mediates adhesion to ICAM-1 (CD54) and C3bi. Mac-1 is expressed on granuloytes, macrophages, natural killer cells, and B-1 cells in the peritoneal and pleural cavities. Mac-1 is up-regulated on neutrophils after activation. This particular clone blocks cell adherence and C3bi binding but does not block cell medited lysis (1,2,3,4,5,6). Applications include flow cytometry, in vitro and in vivo blocking, immunohistochemistry for both paraffin embedded and acetone-fixed frozen sections 1-20 ug/ml (#7). Also used for immunoprecipitation and western blotting.
ncbi acc num :
AAB16869.1
ncbi pathways :
Amoebiasis Pathway 167313!!Amoebiasis Pathway 167191!!Cell Adhesion Molecules (CAMs) Pathway 84481!!Cell Adhesion Molecules (CAMs) Pathway 480!!Cell Surface Interactions At The Vascular Wall Pathway 832066!!Hematopoietic Cell Lineage Pathway 84490!!Hematopoietic Cell Lineage Pathway 489!!Hemostasis Pathway 832039!!Immune System Pathway 831767!!Innate Immune System Pathway 831794