product summary
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company name :
MyBioSource
product type :
chemical
product name :
Picropodophyllotoxin
catalog :
MBS515072
quantity :
5 mg
price :
225 USD
more info or order :
product information
catalog number :
MBS515072
products type :
Inhibitor
products full name :
Picropodophyllotoxin
products short name :
Picropodophyllotoxin
products name syn :
Vatalanib 2 HCl; (5R,5aS,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
purity :
>97% (TLC); NMR (Conforms)
form :
White powder
storage stability :
Store desiccated as supplied at ambient temperature for up to 1 year. Store solutions at -20 degree C for up to 1 month.
other info1 :
CAS Number: 477-47-4. Molecular Formula: C 22 H 22 O 8
other info2 :
Melting Point: 222-224 degree C. Activity: VEGFRK inhibitor. Solubilization: Soluble in DMSO (40 mg/ml)
products categories :
Inhibitors; Biochemicals - Kinase Inhibitors
products description :
IGF1R inhibitor. Scientific Background: Potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP (1). Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC50 ~ 1 nM (1). Displays antiproliferative activity in numerous tumor cell lines, IC50 = 0.05 - 15 uM (2). Exhibits antiangiogenic activitiy (3). Attenuates intimal hyperplasia after vascular injury (4). Active in vivo.
products references :
1. A Girnita et al. Cancer Res. 2004 64:236. 2. A Girnita et al. Clin. Cancer Res. 2006 12:1383. 3. E Menu et al. Int. J. Cancer 2007 121:1857. 4. A Razuvaev et al. J. Vasc. Surg. 2007 46:108.
ncbi mol weight :
414.4
size1 :
5 mg
price1 :
225 USD
size2 :
25 mg
price2 :
575
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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