product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-Lysosomal Associated Membrane Protein 1 (LAMP1)
catalog :
MBS500045
quantity :
0.1 mL
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5H6
reactivity :
human, mouse, rat, cow
application :
western blot
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS500045
products type :
Antibody
products full name :
Anti-Lysosomal Associated Membrane Protein 1 (LAMP1)
products short name :
LAMP1
other names :
lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane glycoprotein 1; lysosome-associated membrane glycoprotein 1; LAMP-1; CD107 antigen-like family member A; lysosome-associated membrane protein 1; lysosomal-associated membrane protein 1; CD107 antigen-like family member A
products gene name :
LAMP1
other gene names :
LAMP1; LAMP1; LAMPA; CD107a; LGP120; LAMP-1
uniprot entry name :
LAMP1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
5H6
host :
Mouse
reactivity :
Bovine, human, mouse, rat
sequence length :
417
specificity :
Specific for the ~64 and 74k lamin A and C proteins.
purity :
Affinity Purified (Affinity purified from tissue culture supernatant)
form :
100 ul in 10mM HEPES (pH 7.5), 150mM NaCl, 100ug per mil BSA and 50% glycerol. Adequate amout of material to conduct 10-mini Western Blots.
storage stability :
Store at -20 degree C in undiluted aliquots; stable for at least 1 year. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
Quality Control: Western blots performed on each lot. WB: 1:5,000
other info1 :
Antigen: Recombinant full length human LAMP1 expressed in and purified from E. Coli. Immunogen Information: Recombinant full length human LAMP1 expressed in and purified from E. coli. Immunogen Species: Human
other info2 :
Species Reactivity Note: The antibody has been directly tested for reactivity in bovine, human, mouse and rat. Biological Significance: Lysosomal Associated Membrane Protein1 (LAMP1) is a protein that is localized primarily in lysosomes but may also be present on late endosomes and the plasma membrane. LAMP1 antibodies are therefore widely used as lysosome markers. It has recently been suggested that lysosomes are activated in microglia in the progression of multiple system atrophy (MSA) and thus play a key role in its pathology (Makioka et al., 2012).
products description :
Affinity purified rabbit polyclonal antibody
products references :
Makioka K, Yamazaki T, Takatama M, Nakazato Y, Okamoto K. (2012) Activation and alteration of lysosomes in multiple system atrophy. Neuroreport. Mar 28;23(5):270-6.
ncbi gi num :
112380628
ncbi acc num :
NP_005552.3
ncbi gb acc num :
NM_005561.3
uniprot acc num :
P11279
ncbi mol weight :
44,882 Da
ncbi pathways :
Lysosome Pathway (99052); Lysosome Pathway (96865); Phagosome Pathway (153910); Phagosome Pathway (153859); Senescence And Autophagy Pathway (198780); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)
ncbi summary :
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Subcellular location: Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome. Note: This protein shuttles between lysosomes, endosomes, and the plasma membrane. Colocalizes with OSBPL1A at the late endosome. Ref.13 Ref.14. Post-translational modification: O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans. Ref.10 Ref.11. Sequence similarities: Belongs to the LAMP family.
size1 :
0.1 mL
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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