catalog number :
MBS494560
products type :
ELISA Kit
products full name :
Cyclic AMP (Direct) ELISA
products short name :
Cyclic AMP
other names :
CAMP, partial; Cathelicidin antimicrobial peptide; cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein; cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein; CAP-18; hCAP-18
other gene names :
CAMP; CAMP; LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39; CAP18; FALL39; CAP-18; hCAP-18
uniprot entry name :
CAMP_HUMAN
storage stability :
All components of this kit, except the conjugate and standard, are stable at 4 degree C until the kit's expiration date. The conjugate and standard should be stored at -20 degree C upon receipt.
other info1 :
Samples: Cells, tissue, saliva, serum, and culture supernates. Detection Range: 0 / 0.78 - 200.00 pmol/mL. Sensitivity: 0.30 pmol/mL in the non-acetylated assay format and 0.039 pmol/mL in the acetylated assay format.
other info2 :
Standards: 6 standards, serially diluted from 1 concentrated standard. Sample Volume: 100 uL of properly prepared unknown / determination. Design: Enzyme immunoassay (ELISA) technique. Assay Description: 2 hour incubation (RT) + 1 hour (RT) = 3 hours total incubation time.
products categories :
Cytokines & Cell Signalling; Research Assays; Assay Categories
products description :
Enzyme immunometric assay (ELISA) for the determination of cyclic AMP in cells and tissue treated with 0.1M HCl, in addition to culture supernates, saliva, and serum. For research use only, not for diagnostic procedures.
ncbi acc num :
CAG46759.1
ncbi mol weight :
19,301 Da
ncbi pathways :
Disease Pathway (530764); Integrated Pancreatic Cancer Pathway (711360); Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway (645267); Phagosomal Maturation (early Endosomal Stage) Pathway (645268); SREBP Signalling Pathway (219802); Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)
ncbi summary :
This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]
uniprot summary :
CAMP: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Belongs to the cathelicidin family. Protein type: Secreted, signal peptide; Cell cycle regulation; Secreted; Vesicle. Chromosomal Location of Human Ortholog: 3p21.3. Cellular Component: extracellular space; specific granule; cell projection; cell wall; cytosol. Molecular Function: protein binding. Biological Process: interaction with host; defense response to Gram-positive bacterium; positive regulation of angiogenesis; innate immune response in mucosa; killing by host of symbiont cells; defense response to bacterium; positive regulation of cell proliferation; antibacterial humoral response; positive regulation of protein amino acid phosphorylation; defense response to Gram-negative bacterium