ELISA/assay

CRP (Canine) ELISA

MBS494422

96 Tests

540 USD

ELISA Kit

CRP (Canine) ELISA

CRP

CRP; C-reactive protein; C-reactive protein; pentraxin 1; C-reactive protein, pentraxin-related

CRP

CRP; CRP; PTX1; PTX1

CRP_HUMAN

Canine

224

2 - 8 degree C

Samples: Canine serum. Detection Range: 0 / 1.5 - 40 ug/mL. Sensitivity: 3.6 ng/mL

Standards: 4 standards, serially diluted from 1 concentrated standard. Sample Volume: 2 uL. Design: Enzyme immunoassay technique. Assay Description: 30 min. (RT) + 30 min. (RT) + 10 min. (RT) = 1 hour, 10 min. total incubation time.

Cytokines & Cell Signalling; Research Assays; Assay Categories

The C-reactive protein assay is intended for the detection of canine C-reactive protein (CRP) in dog serum. C-reactive protein is an acute-phase protein produced by the liver in conditions of inflammation, bacterial infection, or tissue trauma. CRP is useful in determining inflammatory conditions and to monitor the subjects response to treatment. For research use only, not for use in diagnostic procedures.

17975775

AAL48218.2

P02741

10,415 Da

Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); IL6-mediated Signaling Events Pathway (137932); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Selenium Pathway (198825)

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 1q23.2. Cellular Component: extracellular space; growth cone; extracellular region; filopodium. Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; low-density lipoprotein binding; virion binding; cholesterol binding; calcium ion binding. Biological Process: protein polymerization; defense response to Gram-positive bacterium; response to ethanol; negative regulation of vasodilation; wound healing; positive regulation of superoxide release; response to lead ion; response to hypoxia; acute-phase response; opsonization; inflammatory response; complement activation, classical pathway; aging

96 Tests

540 USD