catalog number :
MBS494362
products type :
ELISA Kit
products full name :
sICAM-1 (Monkey) ELISA
products short name :
sICAM-1
other names :
intercellular adhesion molecule 1; Intercellular adhesion molecule 1; intercellular adhesion molecule 1; ICAM-1; cell surface glycoprotein P3.58; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; major group rhinovirus receptor; intercellular adhesion molecule 1; Major group rhinovirus receptor; CD_antigen: CD54
products gene name :
sICAM-1
other gene names :
ICAM1; ICAM1; BB2; CD54; P3.58; ICAM-1
uniprot entry name :
ICAM1_HUMAN
storage stability :
2 - 8 degree C
other info1 :
Samples: Cell Culture Supernatant and serum (baboon, rhesus macaque). Detection Range: 0 / 6.3 - 100 U/mL. Sensitivity: 1.1 U/ml
other info2 :
Standards: 5 standards, serially diluted from 1 concentrated standard. Sample Volume: 10 uL unknown / determination. Design: Enzyme-linked immunosorbent assay. Assay Description: 1 hour incubation (RT) + 10 min. (RT) = 1 hour, 10 min. total incubation time.
products categories :
Immunology; Cytokines & Cell Signalling; Research Assays; Assay Categories
products description :
Enzyme-linked immunosorbent assay for the determination of monkey sICAM-1 in cell culture supernatant and serum (baboon, rhesus macaque). For research use only, not for use in diagnostic procedures.
ncbi acc num :
NP_000192.2
ncbi gb acc num :
NM_000201.2
ncbi mol weight :
57,825 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Cytokine Signaling In Immune System Pathway (366171); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); Extracellular Matrix Organization Pathway (576262); Glucocorticoid Receptor Regulatory Network Pathway (138014)
ncbi summary :
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]
uniprot summary :
ICAM1: a type I membrane protein of the immunoglobulin superfamily. Is a ligand for the leukocyte adhesion LFA-1 protein (Integrin alpha-L/beta-2) and a Rhinovirus receptor. Typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. Its expression is activated by p53 in an NF-kappaB-independent manner. Induced by TNFalpha in a process that involves IKKbeta. Protein type: Membrane protein, integral; Cell adhesion; Immunoglobulin superfamily. Chromosomal Location of Human Ortholog: 19p13.3-p13.2. Cellular Component: extracellular space; focal adhesion; cell surface; membrane; integral to plasma membrane; plasma membrane; immunological synapse; external side of plasma membrane. Molecular Function: viral receptor activity; integrin binding; protein binding; transmembrane receptor activity; receptor activity. Biological Process: extracellular matrix organization and biogenesis; entry of virus into host cell; positive regulation of nitric oxide biosynthetic process; T cell antigen processing and presentation; response to organic cyclic substance; activation of NF-kappaB transcription factor; positive regulation of cellular extravasation; regulation of cell shape; leukocyte adhesion; cellular response to nutrient levels; sensory perception of sound; ovarian follicle development; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; membrane to membrane docking; response to sulfur dioxide; cell adhesion; regulation of leukocyte mediated cytotoxicity; acute inflammatory response to antigenic stimulus; response to drug; regulation of cell adhesion; virion attachment, binding of host cell surface receptor; negative regulation of calcium ion transport; regulation of immune response; cytokine and chemokine mediated signaling pathway; response to amphetamine; cell aging; response to amino acid stimulus; heterophilic cell adhesion; positive regulation of peptidyl-tyrosine phosphorylation; response to ethanol; response to copper ion; positive regulation of actin filament polymerization; positive regulation of vasoconstriction; adhesion to host; cell adhesion mediated by integrin; response to ionizing radiation; leukocyte migration. Disease: Malaria, Susceptibility To