Calcitonin ELISA | MyBioSource MBS494282 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Calcitonin ELISA

catalog :

MBS494282

quantity :

96 Tests

price :

560 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS494282

products type :

ELISA Kit

products full name :

Calcitonin ELISA

products short name :

Calcitonin

other names :

calcitonin; Calcitonin; calcitonin; calcitonin gene-related peptide 1; alpha-type CGRP; calcitonin 1; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha; katacalcin; calcitonin-related polypeptide alpha; Calcitonin carboxyl-terminal peptide; CCP; PDN-21

other gene names :

CALCA; CALCA; CT; KC; CGRP; CALC1; CGRP1; CGRP-I; CALC1; CCP

uniprot entry name :

CALC_HUMAN

reactivity :

Human

sequence length :

141

storage stability :

2 - 8 degree C

other info1 :

Samples: Serum. Sensitivity: 0.7 pg/mL

other info2 :

Standards: 6 calibrators, lyophilized. Sample Volume: 100 uL / determination. Design: Immunoenzymetric assay (ELISA) technique. Controls: 2 controls, lyophilized. Assay Description: 18 hour incubation (2-8 degree C) + 30 min. (RT) = 18 hours, 30 min. total incubation time.

products categories :

Bone & Mineral Metabolism; Research Assays; Assay Categories

products description :

Immunoenzymetric assay (ELISA) for the determination of human Calcitonin (CT) in serum. For research use only, not for use in diagnostic procedures.

ncbi gi num :

179820

ncbi acc num :

AAA58403.1

uniprot acc num :

P01258

ncbi mol weight :

13,898 Da

ncbi pathways :

Amyloids Pathway (366238); Calcitonin-like Ligand Receptors Pathway (106379); Class B/2 (Secretin Family Receptors) Pathway (106378); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); Endothelin Pathway (672453); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637)

ncbi summary :

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]

uniprot summary :

CALCA: Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Belongs to the calcitonin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11p15.2. Cellular Component: extracellular space; cell soma; cytoplasm; extracellular region; terminal button; nucleus. Molecular Function: identical protein binding; protein binding; calcitonin receptor binding; hormone activity; protein complex binding; receptor binding. Biological Process: negative regulation of osteoclast differentiation; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); positive regulation of interleukin-1 alpha production; vasodilation of artery during baroreceptor response to increased systemic arterial blood pressure; response to pain; positive regulation of vasodilation; protein amino acid phosphorylation; G-protein signaling, adenylate cyclase activating pathway; positive regulation of interleukin-8 production; monocyte chemotaxis; leukocyte adhesion; elevation of cytosolic calcium ion concentration; cell-cell signaling; vasculature development; neuropeptide signaling pathway; regulation of blood pressure; receptor internalization; negative regulation of smooth muscle contraction; positive regulation of cAMP biosynthetic process; negative regulation of ossification; feeding behavior; positive regulation of adenylate cyclase activity; negative regulation of blood pressure; positive regulation of macrophage differentiation; inflammatory response; negative regulation of bone resorption; detection of temperature stimulus involved in sensory perception of pain; negative regulation of neurological process; aging; cytosolic calcium ion homeostasis; regulation of heart rate; adenylate cyclase activation; positive regulation of ossification; regulation of systemic arterial blood pressure by neurological process; G-protein coupled receptor internalization; response to heat; endothelial cell proliferation; regulation of inflammatory response; activation of protein kinase activity; endothelial cell migration; negative regulation of transcription, DNA-dependent; embryo implantation

size1 :

96 Tests

price1 :

560 USD

more info or order :

MyBioSource product webpage