ELISA/assay

C-Reactive Protein (hsCRP)  ELISA

MBS494066

96 Tests

305 USD

ELISA Kit

C-Reactive Protein (hsCRP)  ELISA

C-Reactive Protein

C-reactive protein; C-reactive protein; C-reactive protein; pentraxin 1; C-reactive protein, pentraxin-related

hsCRP

CRP; CRP; PTX1; PTX1

CRP_HUMAN

Human

224

2 - 8 degree C

Samples: Human serum. Assay Type: Sandwich. Detection Range: 0 / 100 - 10,000 ng/mL

Standards: 6 calibrators, ready to use. Sample Volume: 10 uL of properly diluted (1:20) unknown / determination. Design: Sandwich enzyme immunoassay (ELISA) technique. Controls: 2 controls, ready to use. Assay Description: 30 min. incubation (RT) + 15 min. (RT) + 15 min. (RT) = 1 hour total incubation time.

Cytokines & Cell Signalling; Research Assays; Assay Categories

Sandwich enzyme immunoassay (ELISA) for the determination of C-Reactive Protein in human serum. For research use only, not for use in diagnostic procedures.

55770842

NP_000558.2

NM_000567.2

10,415 Da

Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); IL6-mediated Signaling Events Pathway (137932); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Selenium Pathway (198825)

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q23.2. Cellular Component: extracellular space; growth cone; extracellular region; filopodium. Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; virion binding; low-density lipoprotein binding; cholesterol binding; calcium ion binding. Biological Process: protein polymerization; defense response to Gram-positive bacterium; response to ethanol; wound healing; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; acute-phase response; response to hypoxia; opsonization; inflammatory response; complement activation, classical pathway; aging

96 Tests

305 USD