This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Tocilizumab (Actemra) (mAb-based) ELISA
catalog :
MBS490287
quantity :
96 Tests
price :
1595 USD
product information
catalog number :
MBS490287
products type :
ELISA Kit
products full name :
Tocilizumab (Actemra) (mAb-based) ELISA
products short name :
[Tocilizumab]
products name syn :
[Actemra]
specificity :
Based on the approach used in calculating the assay cut-off value of anti-drug antibody (ADA) ELISAs, approximately 1-5% of tested samples are expected to generate false-positive ADA response during initial screening analysis. Therefore, further confirmation of the specificity of the ADA activity in the samples, identified as positive, is highly recommended. This is supported also by recent publications. In order to confirm the specificity of the ADA signal, a confirmatory assay (competitive drug inhibition test) is proposed. The confirmatory assay is performed with the Confirmatory Reagent (please inquire). This Confirmatory Reagent is available as a separate product and can be purchased upon request.
storage stability :
Store at 2-8 degree C
app notes :
1 hour incubation (RT) + 1 hour (RT) + 10 min. (RT) = 2 hours, 10 min. total incubation time.
other info1 :
Samples: Serum And Plasma
other info2 :
Intra-assay Precision: <10%. Inter-assay Precision: <10%
products categories :
Immunology; Research Assays; Assay Categories; Drug & Anti-Drug
products description :
Intended Uses: Enzyme immunoassay for the semi-quantitative determination of free antibodies to Cetuximab in serum and plasma. For research use only-not for use in diagnostic procedures. Principle of the Assay: This anti-drug antibody(ies) (ADA) kit is a bridging type ELISA for the determination of free antibodies against the drug Cetuximab in serum and plasma samples. During the first incubation period, ADA in serum or plasma samples are captured by the drug coated on the microtiter wells. After washing away the unbound components from samples, a peroxidase-labelled drug conjugate is added and then incubated. ADA, if present in sample, will make a bridge, with its identical Fab arms, between the drug coated on the well and the other drug molecule labelled with peroxidase. After a second washing step, the bound enzymatic activity is detected by addition of tetramethylbenzidine (TMB) chromogen-substrate. Finally, the reaction is terminated with stop solution. The positive reaction is expected to be related to the presence of ADA in the sample.
size1 :
96 Tests
price1 :
1595 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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