catalog number :
MBS480573
products type :
Recombinant Protein
products full name :
MIC-1, Recombinant Human Protein
products short name :
[MIC-1]
products name syn :
[MIC-1; Placental TGFbeta; Prostate Differentiation Factor]
other names :
[macrophage inhibitory cytokine-1; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor]
products gene name :
[MIC-1]
other gene names :
[GDF15; MIC1; PDF; PLAB; PTGFB; GDF-15; MIC-1; NAG-1; NRG-1]
uniprot entry name :
GDF15_HUMAN
host :
Human cell culture
purity :
> 98% by SDS-PAGE analysis
storage stability :
Store at -20°C.
tested application :
Inhibition Assay
app notes :
Cell inhibition assay with DU-145 cells yields an ED 50 at 2.0 ug/mL
other info1 :
Reconstitution: The lyophilized protein should be reconstituted and aliquoted and stored at -20°C. Endotoxin level: Endotoxin level is less than 0.1 ng per ug (1EU/ug).
products description :
Recombinant Human GDF-15 (H6D Variant)
ncbi acc num :
AAB88673.1
uniprot summary :
GDF15: disulfide-linked. Belongs to the TGF-beta family. Protein type: Secreted; Cytokine; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 19p13.11. Cellular Component: extracellular space; extracellular region. Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding. Biological Process: regulation of apoptosis; cell-cell signaling; regulation of MAPKKK cascade; transforming growth factor beta receptor signaling pathway; signal transduction; cell development