product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-PGE2, Rabbit Polyclonal
catalog :
MBS480053
quantity :
1 mL
price :
170 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, radioimmunoassay, enzyme immunoassay
more info or order :
product information
catalog number :
MBS480053
products type :
Antibody
products full name :
Anti-PGE2, Rabbit Polyclonal
products short name :
PGE2
products name syn :
Anti-Prostaglandin E2
other names :
Prostaglandin E synthase 2; Prostaglandin E synthase 2; prostaglandin E synthase 2; GATE-binding factor 1; gamma-interferon-activated transcriptional element-binding factor 1; mPGE synthase-2; membrane-associated prostaglandin E synthase 2; membrane-associated prostaglandin E synthase-2; microsomal prostaglandin E synthase-2; prostaglandin-H(2) E-isomerase; prostaglandin E synthase 2; Membrane-associated prostaglandin E synthase-2
products gene name :
PGE2
other gene names :
PTGES2; PTGES2; GBF1; GBF-1; PGES2; C9orf15; mPGES-2; C9orf15; PGES2; mPGES-2
uniprot entry name :
PGES2_HUMAN
clonality :
Polyclonal
host :
Rabbit
sequence length :
377
specificity :
Not species specific. May not exhibit utility when using in a rabbit experimental model.
purity :
Not purified
storage stability :
At -80 degree C. AVOID REPEATED FREEZE THAWS.
tested application :
Radioimmunoassay (RIA), ELISA (EIA)
app notes :
RIA: 1:25 dilution. May also have utility in ELISA.
other info1 :
Storage Buffer: PBS; 0.1% Sodium Azide. Sensitivity: 130 pg/assay (IC50). Immunogen: Prostaglandin E2
products description :
Description: This rabbit polyclonal antibody is specific to Prostaglandin E2 and other associated pathway specific arachidonate derived molecules. This antibody is presented as antiserum.
products references :
Levine, L., Measurement of Arachidonic Acid Metabolites by. Radioimmunoassay. In: Manual of Clinical Laboratory. Immunology (3rd Edition). J.L. Fahey, H. Friedman and N.L. Rose. (eds.). Amer. Soc. Microbiol. pp. 685-691 (1986). Granstrom, E. and Lindgren, J.A., Radioimmunoassay of. Prostaglandins and Related Compounds. In: Prostaglandins:. Biology and Chemistry of Prostaglandins and Related. Eicosanoids, P.B. Curtis-Prior, (Ed.) Churchill Livingstone, New. York, pp. 115-12. 6. Powell, W.S., Rapid Extraction of Arachidonic Acid Metabolites From. Biological Samples Using Octadecylsilyl Silica. Meth. Enzymol. 86: 467-476 (1982).
ncbi gi num :
73921741
ncbi acc num :
Q9H7Z7.1
uniprot acc num :
Q9H7Z7
ncbi mol weight :
41,943 Da
ncbi pathways :
Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (366); C20 Prostanoid Biosynthesis Pathway (545299); C20 Prostanoid Biosynthesis Pathway (908107); Eicosanoid Synthesis Pathway (198888); IFN-gamma Pathway (138040); Metabolic Pathways (132956)
ncbi summary :
The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009]
uniprot summary :
PTGES2: Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. Belongs to the GST superfamily. Protein type: Isomerase; EC 5.3.99.3; Lipid Metabolism - arachidonic acid; Membrane protein, integral. Chromosomal Location of Human Ortholog: 9q34.11. Cellular Component: Golgi membrane; mitochondrion; perinuclear region of cytoplasm; integral to membrane; cytosol; nucleus. Molecular Function: DNA binding; glutathione binding; electron carrier activity; lyase activity; heme binding; protein disulfide oxidoreductase activity; prostaglandin-E synthase activity. Biological Process: secretion; cell redox homeostasis; positive regulation of transcription, DNA-dependent; prostaglandin biosynthetic process
size1 :
1 mL
price1 :
170 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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