Anti-CDH17 Mouse mAb | MyBioSource MBS476816 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Anti-CDH17 Mouse mAb

catalog :

MBS476816

quantity :

0.1 mL

price :

335 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

[1D11C6E6]

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

MyBioSource product webpage

image

image 1 :

Western blot analysis using CDH17 mAb against human CDH17 (AA: extra(600-707)) recombinant protein. (Expected MW is 37.9 kDa)

image 2 :

Western blot analysis using CDH17 mAb against HEK293 (1) and CDH17 (AA: extra(600-707))-hIgGFc transfected HEK293 (2) cell lysate.

image 3 :

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CDH17 mouse mAb with DAB staining.

product information

catalog number :

MBS476816

products type :

Antibody

products full name :

Anti-CDH17 Mouse mAb

products short name :

[CDH17]

products name syn :

[CRYA2; CTPP2; HSPB5; CRYAB]

other names :

[cadherin-17; Cadherin-17; cadherin-17; cadherin 17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin]

products gene name :

[CDH17]

other gene names :

[CDH17; CDH17; HPT1; CDH16; HPT-1; LI-cadherin]

clonality :

Monoclonal

isotype :

Mouse IgG1

clone :

[1D11C6E6]

host :

Mouse

reactivity :

Human

purity :

Affinity Purified

form :

Purified antibody from tissue culture in PBS with 0.05% sodium azide

storage stability :

Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

tested application :

Western Blot (WB), Immunohistochemistry (IHC)

app notes :

WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. ICC: N/A. FCM: N/A. ELISA: 1/10000

image1 heading :

Western Blot (WB)

image2 heading :

Western Blot (WB)

image3 heading :

Immunohistochemistry (IHC)

image4 heading :

Immunohistochemistry (IHC)

image4 description :

Immunohistochemical analysis of paraffin-embedded colon tissues using CDH17 mouse mAb with DAB staining.

other info1 :

Conjugation: Unconjugated. Modification: Unmodification. Immunogen: Purified recombinant fragment of human CDH17 (AA: extra(600-707)) expressed in E. Coli. Subcellular location: Cell membrane, Membrane

products description :

Swiss-Prot Acc.Q12864.This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

ncbi gi num :

221316595

ncbi acc num :

NP_001138135.1

ncbi gb acc num :

NM_001144663.1

uniprot acc num :

Q12864

ncbi mol weight :

92.2kDa

ncbi summary :

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

uniprot summary :

CDH17: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 8q22.1. Cellular Component: basolateral plasma membrane; plasma membrane. Molecular Function: integrin binding; proton-dependent oligopeptide secondary active transmembrane transporter activity; transporter activity. Biological Process: calcium-dependent cell-cell adhesion; cell adhesion; cell surface receptor linked signal transduction leading to integrin activation; homophilic cell adhesion; integrin-mediated signaling pathway; oligopeptide transport

size1 :

0.1 mL

price1 :

335 USD

more info or order :

MyBioSource product webpage