product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-C17orf53 Mouse mAb
catalog :
MBS476655
quantity :
0.1 mL
price :
335 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[7E1-B11-F3]
reactivity :
human
application :
western blot
more info or order :
image
image 1 :
Western blot detection of C17orf53 in Jurkat, A549, MCF7 and Hela cell lysates using C17orf53 mouse mAb (1:1000 diluted). Predicted band size:70KDa. Observed band size:70KDa.
product information
catalog number :
MBS476655
products type :
Antibody
products full name :
Anti-C17orf53 Mouse mAb
products short name :
[C17orf53]
products name syn :
[C17orf53; Chromosome 17 open reading frame 53; CQ053_HUMAN; FLJ11594; Hypothetical protein LOC78995; MGC3130; Uncharacterized protein C17orf53]
other names :
[uncharacterized protein C17orf53 isoform 2; Uncharacterized protein C17orf53; uncharacterized protein C17orf53; chromosome 17 open reading frame 53]
products gene name :
[C17orf53]
other gene names :
[C17orf53; C17orf53]
clonality :
Monoclonal
isotype :
IgG2a
clone :
[7E1-B11-F3]
host :
Mouse
reactivity :
Human
sequence length :
646
purity :
Affinity purified
form :
Purified antibody in PBS with 0.05% sodium azide.
storage stability :
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycles.
tested application :
Western Blot (WB)
app notes :
Western Blot (WB): 1/500-1/2000. ELISA (EIA): 1/1000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Purified recombinant fragment of human C17ORF53 (AA: 282-527) expressed in E Coli. Conjugation: Unconjugated. Modification: Unmodification
products description :
Entrez Summary: C17orf53 (chromosome 17 open reading frame 53) is a 647 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1, 200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
ncbi gi num :
284005249
ncbi acc num :
NP_001164722.1
ncbi gb acc num :
NM_001171251.2
uniprot acc num :
Q8N3J3
ncbi mol weight :
69.8 kDa
uniprot summary :
C17orf53: 3 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 17q21.31
size1 :
0.1 mL
price1 :
335 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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