catalog number :
MBS4751406
products full name :
Anti-Plexin A1 Rabbit pAb
products short name :
[Plexin A1]
products name syn :
[NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1;]
other names :
[plexin-A1; Plexin-A1; plexin-A1; plexin A1; Semaphorin receptor NOV]
products gene name :
[PLXNA1]
other gene names :
[PLXNA1; PLXNA1; NOV; NOVP; PLXN1; PLEXIN-A1; NOV; PLXN1]
reactivity :
Human, Mouse, Rat
specificity :
Plexin A1 Antibody detects endogenous levels of total Plexin A1
purity :
Affinity Chromatography
form :
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
storage stability :
Store at 4 degree C for short term. Store at-20 degree C for long term. Avoid freeze/thaw cycle.
tested application :
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
app notes :
WB: 1:500-1:2000. ICC/IF: 1:50-1:200. FC/FACS: 1:50
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human Plexin A1. Conjugation: Unconjugated. Modification: Unmodification
other info2 :
Subcellular location: Cell membrane, Membrane.
products description :
Plays a role in axon guidance, invasive growth and cell migration.
ncbi acc num :
NP_115618.3
ncbi gb acc num :
NM_032242.3
ncbi pathways :
Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688); CRMPs In Sema3A Signaling Pathway (119525); Developmental Biology Pathway (477129); Other Semaphorin Interactions Pathway (119526); SEMA3A-Plexin Repulsion Signaling By Inhibiting Integrin Adhesion Pathway (119523); Sema3A PAK Dependent Axon Repulsion Pathway (119524); Semaphorin Interactions Pathway (119519)
uniprot summary :
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm ().