catalog number :
MBS4751397
products full name :
Anti-Biglycan Rabbit pAb
products short name :
[Biglycan]
products name syn :
[Biglycan; DSPG1; PG S1; PGI; SEMDX; SLRR1A]
other names :
[biglycan preproprotein; Biglycan; biglycan; biglycan; Bone/cartilage proteoglycan I; PG-S1]
products gene name :
[BGN]
other gene names :
[BGN; BGN; PGI; MRLS; DSPG1; PG-S1; SEMDX; SLRR1A; SLRR1A]
reactivity :
Human, Mouse, Rat
purity :
Affinity Chromatography
form :
Rabbit IgG Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.!!Subcellular location Extracellular matrix, Secreted
storage stability :
Store at 4 degree C for short term. Store at-20 degree C for long term. Avoid freeze/thaw cycle.
tested application :
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
app notes :
WB: 1:500-1:2000. IP: 1:50. FC/FACS: 1:100
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: A synthesized peptide derived from human Biglycan. Conjugation: Unconjugated. Modification: Unmodification. Target: Biglycan Antibody detects endogenous levels of total Biglycan
products description :
May be involved in collagen fiber assembly.
ncbi acc num :
NP_001702.1
ncbi gb acc num :
NM_001711.5
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); CS/DS Degradation Pathway (645311); Chondroitin Sulfate Biosynthesis Pathway (645309); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Dermatan Sulfate Biosynthesis Pathway (645310); Disease Pathway (530764); ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262); Glycosaminoglycan Metabolism Pathway (645297); Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway (645304)
ncbi summary :
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015]
uniprot summary :
May be involved in collagen fiber assembly.