antibody

Anti-Growth Hormone Rabbit pAb

MBS4750794

0.1 mL

335 USD

polyclonal

rabbit

nonconjugated

western blot, immunohistochemistry, immunoprecipitation

Antibody

Anti-Growth Hormone Rabbit pAb

[Growth Hormone]

[GH1; Growth hormone 1; hGH-N; IGHD1B; Pituitary growth hormone; RNGHGP; Somatotropin]

[somatotropin isoform 1; Somatotropin; somatotropin; growth hormone 1; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone]

[GHN]

[GH1; GH1; GH; GHN; GH-N; GHB5; hGH-N; IGHD1B; GH; GH-N]

Polyclonal

IgG

Rabbit

Human

217

Growth Hormone Antibody detects endogenous levels of total Growth Hormone

Affinity Chromatography

Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Store at 4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Western Blot (WB), Immunhistochemistry (IHC), Immunoprecipitation (IP)

WB: 1:500-1:2000. IHC: 1:50-1:200. IP: 1:20

Western Blot (WB)

Immunohistochemistry (IHC)

Immunogen: A synthesized peptide derived from human Growth Hormone. Modification: Unmodification

Subcellular Location: Secreted

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

13027812

NP_000506.2

NM_000515.4

P01241

25kDa

Adipogenesis Pathway (198832); Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Endochondral Ossification Pathway (198812); Growth Hormone Receptor Signaling Pathway (477128); Immune System Pathway (106386); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Metabolism Of Proteins Pathway (106230)

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

0.1 mL

335 USD