product summary
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company name :
MyBioSource
product type :
antibody
product name :
beta-Tubulin
catalog :
MBS470004
quantity :
0.1 mL
price :
170 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS470004
products type :
Antibody
products full name :
beta-Tubulin
products short name :
beta-Tubulin
products name syn :
Tubulin beta
clonality :
Monoclonal
isotype :
IgG1
host :
Mouse
reactivity :
Human, Rat, Mouse
specificity :
This antibody detects a 50 kDa* protein corresponding to the molecular mass of b-Tubulin on SDS-PAGE immunoblots of purified brain tubulin, mouse brain tissue, rat PC12 cells, and human A431 and SH-SY5Y cells.
purity :
Protein A Purified
form :
Mouse monoclonal antibody purified with protein A chromatography is supplied in 100ml phosphate-buffered saline, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide.
storage stability :
Store at -20 degree C. Do not aliquot. Stable for 1 year.
tested application :
ELISA, Western Blot, Immunocytochemistry
app notes :
ELISA: 1:2000. Immunocytochemistry: 1:200. Western Blot: 1:1000
other info1 :
Immunogen: Clone (M154) was generated from purified porcine brain tubulin.
products description :
Microtubules (MTs) are cytoskeletal elements that play an essential role in cell division and cytoplasmic organization. MTs are dynamic polymers of a/b-tubulin heterodimers. At least two populations of MTs, called dynamic and stable according to their rates of turnover, are readily distinguishable in cells. The proteins associated with MTs (MAPs) are among the best-known factors that regulate MT dynamics and stability. In addition, a variety of different post-translational modifications may also regulate MT dynamics and stability. Phosphorylation is one of these modifications and it can occur on serine, threonine, and tyrosine residues in b-tubulin isoforms. Multiple kinases can phosphorylate Ser-444 at the C-terminus of bIII-tubulin in vitro. Unphosphorylated Ser-444 in bIII-tubulin is an early marker for cells of neuronal lineage, while phosphorylation of Ser-444 is upregulated after neuronal maturation and may preferentially occur in assembled MTs. By contrast, Cdk1 phosphorylation of Ser-172 in b-tubulin occurs in mitotic cells and may impair tubulin incorporation into microtubules.
products references :
Fourest-Lieuvin, A. et al. (2006) Mol. Biol. Cell. 17(3):1041. Westermann, S. & Weber, K. (2003) Nat. Rev. Mol. Cell. Biol. 4:938. Fanarraga, M.L. et al. (1999) Eur. J. Neurosci. 11:517. Diaz-Nido, J. et al. (1990) J Biol. Chem. 265(23):13949.
size1 :
0.1 mL
price1 :
170 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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