product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti CD117/c-Kit (CT) Polyclonal antibody
catalog :
MBS462247
quantity :
0.1 mg
price :
275 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS462247
products type :
Antibody
products full name :
Rabbit anti CD117/c-Kit (CT) Polyclonal antibody
products short name :
CD117 (kit)
products name syn :
Rabbit anti--c-Kit (CT); Kit Protein; c-Kit; CD117 antigen; SCFR; PBT
products gene name :
CD117 (kit)
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat, Canine
specificity :
This antibody recognizes CD17/c-Kit protein. It crossreacts to human, mouse and rat. The other species were not tested.
purity :
The Rabbit IgG is purified by Epitope Affinity Purification.
form :
This affinity purified antibody is supplied in sterile Phosphate-buffered saline (pH7.2) containing antibody stabilizer
concentration :
Size: 100 ug/200 ul
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C.The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
tested application :
ELISA, Western Blot, Immunohistochemistry
app notes :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunoprecipitation: 2-5 ug/ml. Immunohistochemistry: 2-5 ug/ml
other info1 :
Antigen Preparation: A synthetic peptide derived from N-terminus of Kit protein. This sequence is identical in human, rat, mouse and dog origins.
other info2 :
Positive Control: Jurkat cell. Cellular Location: Membrane/Cytoplasmic
products description :
The c-Kit proto-oncogene encodes a 145 kDa transmembrane receptor (CD117) with tyrosine kinase activity that is structurally related to platelet-derived growth factor. C-Kit/CD117 antigen is expressed on almost all hematopoietic stem and progenitor cells. c-Kit regulates a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. C-kit plays an important role in hematopoiesis, melanogenesis, and gametogenesis.
products references :
Li J et al. Expression of c-Kit receptor tyrosine kinase and effect on beta-cell development in the human fetal pancreas. Am J Physiol Endocrinol Metab 293:E475-83 (2007).
ncbi mol weight :
~145 kDa
size1 :
0.1 mg
price1 :
275 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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