product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti Phospho-FAK (pTyr 576)
catalog :
MBS462199
quantity :
0.1 mg
price :
280 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, immunohistochemistry
more info or order :
product information
catalog number :
MBS462199
products type :
Antibody
products full name :
Rabbit anti Phospho-FAK (pTyr 576)
products short name :
FAK (pY576)
products name syn :
Rabbit anti-Phospho-FAK (pY576); Focal Adhesion Kinase (FAK); FAK1; FADK; pp125FAK; PTK2.
products gene name :
FAK (pY576)
host :
Rabbit
reactivity :
Human; Rat; Mouse
specificity :
This antibody recognizes FAK (pY576) with a phosphorylated site at Tyrosine 576. It does not crossreact with non-phosphospecific peptide.
purity :
The Rabbit IgG is purified by site-modified Epitope Affinity Purification.
form :
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
concentration :
0.5mg/ml
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
tested application :
ELISA, Western Blot, Immunohistochemistry
app notes :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunoprecipitation: 2-5 ug/ml. Immunohistochemistry: 1:100 tested
other info1 :
Volume: 0.2ml. Antigen Preparation: A synthetic peptide surrounding to the epitope -STYYKA- with a phosphorylation site at Tyrosine 576 of human FAK protein. This sequence is identical among human, mouse and rat.
other info2 :
Positive Control: Conditioned 3T3 cell lysate. Cellular Location: Cytoplasmic
products description :
Focal adhesion kinase (FAK) gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinase but lacks significant sequence similarity to kinase from other subfamilies. Activation by phosphorylation of Y397, Y576/577 and Y863 of FAK protein may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Increased FAK expression has been correlated with the enhanced motility and invasiveness of human tumor cells, as well as with promoting increased cell proliferation
products references :
Leu TH, et al. Tyr-863 phosphorylation enhances focal adhesion kinase autophosphorylation at Tyr-397. Oncogene. 2002 Oct 10;21 (46):6992-7000.
ncbi mol weight :
125 kDa
size1 :
0.1 mg
price1 :
280 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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