product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti Phospho- ERK1/2 (pThr202/pTyr204)
catalog :
MBS462193
quantity :
0.1 mg
price :
415 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, immunohistochemistry
more info or order :
product information
catalog number :
MBS462193
products type :
Antibody
products full name :
Rabbit anti Phospho- ERK1/2 (pThr202/pTyr204)
products short name :
ERK1/2 (P44-MAPK) (pT202/pY204)
products name syn :
Rabbit anti--ERK1/2 (pT202/pY204) Phosphospecific; Extracellular signal-regulated kinase; ERK1; Mitogen activated protein kinase 3; MAPK3; p44/42 MAPK; ERK/MAPK
other names :
Extracellular signal-regulated kinase 1
products gene name :
ERK1/2 (P44-MAPK) (pT202/pY204)
host :
Rabbit
reactivity :
Human, Mouse, Rat, Chicken, Canine
specificity :
This antibody recognizes ERK1/2 (pT202/pY204) with the dual phosphorylation sites. It does not cross-react with non-phosphospecific peptide.
purity :
The Rabbit IgG is purified by site-modified Epitope Affinity Purification.
form :
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
concentration :
Size: 100 ug/200 ul
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
tested application :
ELISA, Western Blot, Immunohistochemistry
app notes :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunoprecipitation: 2-5 ug/ml
other info1 :
Antigen Preparation: A synthetic peptide derived from epitope -LTEYV- with the dual phosphorylation sites Thr202 and Tyr204 of ERK1/2 protein from human, rat, mouse and dog origins.
other info2 :
Positive Control: UV treated 3T3 cells. Cellular Location: Cytoplasmic
products description :
The extracellular signal-regulated kinases ½ (ERK1/2) are also known as MAPK (Mitogen-activated protein kinases) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (ERK1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer. The phosphorylation of MAPK at Thr202 and Tyr 204 are correlated to the progression and metastatic potential of tumor cells.
products references :
M. Klink, et al. Ovarian Cancer Cells Modulate Human Blood Neutrophils Response to Activation In Vitro. Clinical Immunology, 68 (3), 328-336. 2008.
ncbi gi num :
1169549
ncbi mol weight :
42/44 kDa
ncbi pathways :
Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Salmonella Infection Pathway 375172!!Salmonella Infection Pathway 375149
size :
0.1 mg
price :
415 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!