catalog number :
MBS462141
products full name :
Rabbit anti STAT5 Polyclonal antibody
products short name :
STAT5
products name syn :
Rabbit anti--STAT5; Signal transducer and activator of transcription 5 (STAT5)
other names :
STAT5; STAT5
products gene name :
STAT5
other gene names :
stat5a
reactivity :
Human, Rat, Mouse, Bovine, Canine
specificity :
This antibody recognizes STAT5. It does not crossreact to other STAT proteins
purity :
The Rabbit IgG is purified by Epitope Affinity Purification.
form :
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
concentration :
Size: 100 ug/200 ul
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
tested application :
ELISA, Western Blot, Immunohistochemistry
app notes :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunoprecipitation: 2-5 ug/ml. Immunohistochemistry: 1:100
other info1 :
Antigen Preparation: A synthetic peptide surrounding to the C-terminus of STAT5 protein from human, mouse and rat origins.
other info2 :
Positive Control: Mouse liver. Cellular Location: Nuclear
products description :
STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. STAT5 is tyrosine phosphorylated in response to IL-2, IL-3, IL-7, IL-15, GM-CSF, growth hormone, prolactin, erythropoietin and thrombopoietin. Serine phosphorylation is also required for maximal transcriptional activity. NCoA-1/SRC-1 acts as a co-activator for both the a- and b-isoforms of STAT5.
products references :
Lin, J.X., et al. Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells. J. Biol Chem. 271: 10738, 2006
ncbi acc num :
NP_001083890.1
ncbi gb acc num :
NM_001090421.1