product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti Saposin antibody
catalog :
MBS462127
quantity :
0.1 mg
price :
265 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA
more info or order :
image
image 1 :
MyBioSource MBS462127 image 1
product information
catalog number :
MBS462127
products type :
Antibody
products full name :
Rabbit anti Saposin antibody
products short name :
[SAPOSIN (PSAP)]
products name syn :
[Rabbit anti-Saposin (IN)]
products gene name :
[SAPOSIN (PSAP)]
clonality :
polyclonal
host :
rabbit
reactivity :
Human
specificity :
This antibody recognizes ~70 kDa of human Prosaposin protein. It also reacts with mouse and rat. The other species are not tested.
purity :
The Rabbit IgG is purified by specific Epitope Affinity Purification.
form :
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
tested application :
ELISA, Western Blot
app notes :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunoprecipitation: 2-5 ug/ml. Optimal dilutions should be determined by researchers for the specific applications.
image1 heading :
Testing Data
other info1 :
Antigen Preparation: A synthetic peptide corresponding to internal sequence (within 300-360aa) of human Saposin.
products description :
The Saposin family includes four structurally related proteins, saposin A, B, C, and D which are ~80 aa small acidic acitvator proteins with specificities for glycosphingolipid (GSL) hydrolases. They are derived from a single precursor, prosaposin. In both humans and mice, prosaposin/saposin deficiencies lead to severe neurological deficits. Saposins are processed from prosaposin in the late endosome and lysosome, and their stability is maintained by three disulfide bridges. The post-modified prosoposin is an ~70 kDa form which subsequently undergoes partial proteolysis to produce saposin A, B, C, and D, each proteins are between 12-14 kDa in mass.
products references :
Ying Sun et al. Combined saposin C and D deficiencies in mice lead to a neuronopathic phenotype, glucosylceramide and -hydroxy ceramide accumulation, and altered prosaposin trafficking. Human Molecular Genetics 2007 16 (8):957-971.
ncbi mol weight :
70 kDa
size1 :
0.1 mg
price1 :
265 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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