product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti Phospho- STAT1 (pTyr 701)
catalog :
MBS462111
quantity :
0.1 mg
price :
305 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
Xenopus laevis
application :
western blot, ELISA, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS462111
products type :
Antibody
products full name :
Rabbit anti Phospho- STAT1 (pTyr 701)
products short name :
STAT1 (pY701)
products name syn :
Rabbit anti-Phospho-STAT1 (pY701); Signal transducer and activator of transcription 1 (STAT1)
other names :
signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1, 91kDa
products gene name :
STAT1 (pY701)
other gene names :
stat1; XStat1
host :
Rabbit
reactivity :
Human, Rat, Mouse
specificity :
This antibody recognizes STAT1 (pY701) with a phosphorylated sites of Tyr701. It does not cross-react with non-phosphospecific peptide.
purity :
The Rabbit IgG is purified by site-modified Epitope Affinity Purification.
form :
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
concentration :
Size: 100 ug/200 ul
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
tested application :
ELISA, Western Blot, Immunohistochemistry
app notes :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunoprecipitation: 2-5 ug/ml. Immunohistochemistry: 1:50
other info1 :
Antigen Preparation: A synthetic peptide surrounding to the epitope -TGYIK-- with phosphorylation sites at Tyr701 of STAT1 protein from human, mouse and rat origins.
other info2 :
Positive Control: GH stimulated mouse liver. Cellular Location: Nuclear
products description :
STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. The phosphorylation of STAT1 at Tyr701 induces STAT1 dimerization, nuclear translocation and DNA binding. STAT 1 is activated by a number of different ligands, including IFN, EGF, PDGF and IL6. Tyrosine 701 phosphorylation impairment results in loss of STAT 1 functions.
products references :
Tong R Wu, et al. SHP-2 Is a Dual-specificity Phosphatase Involved in Stat1 Dephosphorylation at Both Tyrosine and Serine Residues in Nuclei, J. Biol. Chem., Vol. 277, Issue 49, 47572-47580, December 6, 2002
ncbi gi num :
147904732
ncbi acc num :
NP_001082256.1
ncbi gb acc num :
NM_001088787.1
ncbi mol weight :
91 kDa
ncbi pathways :
Jak-STAT Signaling Pathway (84661); Jak-STAT Signaling Pathway (488); Toll-like Receptor Signaling Pathway (117264); Toll-like Receptor Signaling Pathway (487)
size1 :
0.1 mg
price1 :
305 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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