product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti MMP-2 Polyclonal antibody
catalog :
MBS462081
quantity :
0.1 mg
price :
350 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, chicken
application :
western blot, ELISA, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS462081
products type :
Antibody
products full name :
Rabbit anti MMP-2 Polyclonal antibody
products short name :
MMP-2
products name syn :
Rabbit anti-MMP-2; Matrix Metalloproteinase 2 (MMP2); Gelatinase A; 72 kDa type IV collagenase precursor
other names :
MMP-2; MMP-2; 72 kDa type IV collagenase; MMP-2; gelatinase A; 72 kDa gelatinase; matrix metalloproteinase 2; matrix metalloproteinase-2; matrix metallopeptidase 2
products gene name :
MMP-2
other gene names :
Mmp2; Mmp2; MMP-2
uniprot entry name :
Q9JHC2_RAT
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Rat, Mouse, Chicken, Canine
specificity :
This antibody recognizes ~62 and 72 kDa of human MMP2 protein. This antibody reacts with human, rat, mouse. The other species are not tested.
purity :
The Rabbit IgG is purified by Epitope Affinity Purification.
form :
This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer
concentration :
Size: 100 ug/200 ul
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C -8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
tested application :
ELISA, Western Blot, Immunohistochemistry
app notes :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunoprecipitation: 2-5 ug/ml. Immunohistochemistry: 2-5 ug/ml
other info1 :
Antigen Preparation: A synthetic peptide corresponding to C-term of human MMP2. This sequence is identical among human, rat, mouse, chicken, dog and bovine.
other info2 :
Positive Control: Breast cancer. Cellular Location: Cytoplasmic and extracellular matrix
products description :
Matrix metalloproteinases (MMPs) belong to a family of proteinases that target many extracellular matrix proteins including additional proteinases, growth factors, cell surface receptors and adhesion molecules. MMPs contain common domain structures that include a signal sequence, a propeptide, a catalytic domain, and a hemopexin-like (Hpx) domain. The MMP activity requires proteolytic cleavage of MMPs in order to generate activie MMPs by release of the inhibitory propeptide domain from the whole molecules. MMP-2, MMP-3, MMP-7, MMP-9 and MMP-13 have been characterized as important factors for normal tissue remodeling during embryo development and wound healing, tumor invasion, angiogenesis, carcinogenesis and apoptosis. MMP activities are correlated with cancer metastatic process.
products references :
Brigitte Lelongt, et al. Matrix Metalloproteinases MMP2 and MMP9 Are Produced in Early Stages of Kidney Morphogenesis but Only MMP9 Is Required for Renal Organogenesis In Vitro. J. Cell Biol. 1997. 136 (6), 1363-1373.
ncbi gi num :
8050250
uniprot acc num :
Q9JHC2
ncbi mol weight :
62kDa, 72 kDa
ncbi pathways :
Bladder Cancer Pathway (83503); Bladder Cancer Pathway (527); GnRH Signaling Pathway (83483); GnRH Signaling Pathway (502); IL-3 Signaling Pathway (198504); Leukocyte Transendothelial Migration Pathway (83475); Leukocyte Transendothelial Migration Pathway (494); Matrix Metalloproteinases Pathway (198492); Pathways In Cancer (83493)
ncbi summary :
plays important roles in wound healing, angiogenesis, platelet aggregation, and tumor metastasis; mediates the response of the intrinsic glomerular mesangial cell to inflammatory stimuli [RGD]
size1 :
0.1 mg
price1 :
350 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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