product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti ER (pSer 305), Phosphospecific
catalog :
MBS462046
quantity :
0.1 mg
price :
345 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS462046
products type :
Antibody
products full name :
Rabbit anti ER (pSer 305), Phosphospecific
products short name :
ER (pS305) (phosphospecific)
products name syn :
Rabbit anti-ER (pSer305) (Phosphospecific); Estrogen Receptor
products gene name :
ER (pS305) (phosphospecific)
host :
Rabbit
reactivity :
Human, Mouse
specificity :
This antibody recognizes ~67 kDa of human estrogen receptor at the phosphorylation site of Ser 305. It does not cross react to non-phosphorylated peptide. This antibody reacts with human. The other species are not tested.
purity :
The Rabbit IgG is purified by Site-specific Epitope Affinity Purification.
form :
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer
concentration :
Size: 100 ug/200 ul
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
tested application :
ELISA, Western Blot
app notes :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunoprecipitation: 2-5 ug/ml. Immunohistochemistry: 1:200
other info1 :
Antigen Preparation: A synthetic peptide surrounding the epitope -KNSLA- with a phosphorylation site of Ser305 of human estrogen receptor.
other info2 :
Positive Control: MCF-7. Cellular Location: Nuclear
products description :
ER (estrogen receptor) belongs to a member of the steroid receptor superfamily. It contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by its phosphorylation at multiple sites, such as serine 104, 106, 118, 167 and 305. Phosphorylation of certain serine at ER may relate to breast cancer process and on-going treatment.
products references :
Dutertre M, Smith CL. 2003. Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains. Mol Endocrinol 17:1296-314.
ncbi mol weight :
67 kDa
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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