product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti eNOS antibody
catalog :
MBS462042
quantity :
0.1 mg
price :
350 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
application :
western blot, ELISA, immunohistochemistry
more info or order :
product information
catalog number :
MBS462042
products type :
Antibody
products full name :
Rabbit anti eNOS antibody
products short name :
eNOS
products name syn :
Rabbit anti-eNOS; Endothelial Nitric Oxide Synthase (eNOS); Nitric oxide synthase 3 (NOS3)
other names :
eNOS protein; ENOS protein
products gene name :
eNOS
other gene names :
eNOS
uniprot entry name :
A6H544_CALJA
host :
Rabbit
reactivity :
Human, Rat, Mouse, Dog, Pig, Cow
specificity :
This antibody only recognizes ~130 kDa of human eNOS. It does not detect human inducible NOS or rat brain NOS. It also reacts with mouse and rat eNOS protein. The other species are not tested.
purity :
The Rabbit IgG is purified by Epitope Affinity Purification.
form :
This affinity purified antibody is supplied in sterile phosphatebuffered saline (pH7.2) containing antibody stabilizer
concentration :
Size: 100 ug/200 ul
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
tested application :
ELISA, Western Blot, Immunohistochemistry
app notes :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunoprecipitation: 2-5 ug/ml. Immunohistochemistry: 1:50 ug/ml
other info1 :
Antigen Preparation: A synthetic peptide corresponding to the internal sequence (residing in 550-650aa) of human eNOS protein. This sequence is identical among human, rat, mouse, bovine origins.
other info2 :
Positive Control: placenta. Cellular Location: Cytoplasmic
products description :
NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be enhanced through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. There are three types of NOS: two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II). iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells. Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels. The phosphorylation of eNOS by Protein kinase C was associated with an increase in NO production.
products references :
Louis J. Ignarro, Functional interaction of endothelial nitric oxide synthase with a voltage-dependent anion channel. Proc Natl Acad Sci U S A. 99 (20): 13108-13113, 2002.
ncbi gi num :
148913721
uniprot acc num :
A6H544
ncbi mol weight :
140 kDa
ncbi pathways :
Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Salmonella Infection Pathway 375172!!Salmonella Infection Pathway 375149
size :
0.1 mg
price :
350 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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