catalog number :
MBS460475
products full name :
Mouse anti-ACC Carboxylase 1 Monoclonal Antibody
products short name :
[ACC Carboxylase 1]
products name syn :
[Acetyl-CoA Carboxylase; ACC]
products gene name :
[ACC]
specificity :
This antibody recognizes high molecular weight of ACC protein. It reacts with human, rat and mouse. The other species are not tested.
purity :
The mouse IgG is purified by IgG1 affinity purification
form :
This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at –20 degree C to –70 degree C. The antibodies can be stored at 2 degree C to 8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
tested application :
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P), Immunoprecipitation (IP), Western Blot (WB)
app notes :
Western Blot: 0.5-2 ug/ml. ELISA: 0.1-1 ug/ml. Immunoprecipitation: 2-5 ug/ml. IHC-P: 2-5 ug/ml. Positive Control: K562. Cellular Location: Cytoplasmic. Optimal dilutions should be determined by researchers for the specific applications.
image1 heading :
Western Blot
other info1 :
Antigen Preparatation: A synthetic peptide derived from C-terminus of Acetyl-CoA Carbvoxylase protein.
products description :
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which
catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC
forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is
under long term control at the transcriptional and translational levels and under short term regulation by the
phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA.
Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found
for this gene.
ncbi mol weight :
~280 kDa