Mouse anti GLEPP-1 Monoclonal Antibody | MyBioSource MBS460465 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Mouse anti GLEPP-1 Monoclonal Antibody

catalog :

MBS460465

quantity :

0.1 mg

price :

285 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

[5F3F8]

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

The human kidney tissue stained with Mouse GLEPP-1 monoclonal antibody (MBS460465) at 1:100 using AEC chromogen. (Note: formalin-fixed, paraffin-embedded sections need 15 minutes heat-induced epitope retrieval in 10 mM citrate buffer, pH 6.0, and 30 minutes incubation at room temperature with the primary antiibody).

product information

catalog number :

MBS460465

products type :

Antibody

products full name :

Mouse anti GLEPP-1 Monoclonal Antibody

products short name :

[GLEPP-1]

products name syn :

[Glomerular Epithelial Protein 1; NPHS6; PTPU2; GLEPP1; PTP-OC; PTP-U2; PTPROT; R-PTP-O]

products gene name :

[GLEPP-1]

clonality :

Monoclonal

isotype :

IgG2b, kappa

clone :

[5F3F8]

host :

Mouse

reactivity :

Human, Rat, Mouse

specificity :

The Kit for Giardia intestinalis (G.intestinalis) genomes is designed for the in vitro quantification of G.intestinalis genomes. The kit is designed to have a broad detection profile. Specifically, the primers represent 100% homology with over 95% of the NCBI database reference sequences available at the time of design. The dynamics of genetic variation means that new sequence information may become available after the initial design. Periodically reviews the detection profiles of our kits and when required releases new versions.

purity :

This Mouse IgG is purified by Istoyping-specific Affinity Purification

form :

Supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.

storage stability :

The antibodies are stable for 12 months from date of receipt when stored at -20°C to -70°C. The antibodies can be stored at 2°C-8°C for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.

tested application :

Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)

app notes :

Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml. Immunohistochemistry: 1:100. Optimal dilutions should be determined by researchers for the specific applications.

image1 heading :

Immunohistochemistry (IHC)

products description :

Background/Introduction: Giardiasis is a major diarrheal disease found throughout the world. The flagellate protozoan Giardia intestinalis (also known as Giardia lamblia), its causative agent, is the most commonly identified intestinal parasite in the United States and the most common protozoal intestinal parasite isolated worldwide. Giardiasis usually represents a zoonosis with cross-infectivity between animals and humans. Giardia has been isolated from the stools of beavers, dogs, cats, rodents, sheep, and cattle. Within Giardia intestinalis there are 7 assemblages, A, B, C, D, E, F, and the more rarely occuring G. Of these, only assemblages A and B can infect humans, whereas, a range of animals can be infected by assemblages A-G. Giardiasis is caused by ingestion of Giardia cysts, which retain viability in cold water for as long as 2-3 months. The infective dose is low in humans; 10-25 cysts are capable of causing clinical disease in 8 of 25 subjects. Ingestion of more than 25 cysts results in a 100% infection rate. After ingestion of cysts, excystation, trophozoite multiplication, and colonization of the upper small bowel occur. Most infections result from fecal-oral transmission or ingestion of contaminated water. Contaminated food is a less common etiology. Person-to-person spread is common, with 25% of family members with infected children themselves becoming infected. Most infections are asymptomatic, and the attack rate for symptomatic infection in the natural setting varies from 5-70%. Giardia is found in healthy people in endemic areas and in symptomatic carrier states with high numbers of cysts excreted in stools common. Predisposing factors to symptomatic infection include hypochlorhydria, various immune system deficiencies, blood group A, and malnutrition. The incubation period averages 1-2 weeks, with a mean of 9 days. The average duration of symptoms in all ages ranges from 3-10 weeks.

ncbi mol weight :

~130 kDa

ncbi pathways :

Primary Focal Segmental Glomerulosclerosis FSGS Pathway (920976); Signaling Events Mediated By Stem Cell Factor Receptor (c-Kit) Pathway (138068)

size1 :

0.1 mg

price1 :

285 USD

more info or order :

MyBioSource product webpage