catalog number :
MBS460001
products full name :
Mouse anti cAMP Monoclonal antibody
products short name :
cyclic adenosine monophosphate (cAMP)
products name syn :
Mouse anti-cAMP; 3’; 5’-Cyclic Adenosine Monophosphate (c-AMP)
other names :
CAMP; Cathelicidin antimicrobial peptide; cathelicidin antimicrobial peptide; OTTHUMP00000164805; 18 kDa cationic antimicrobial protein; cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein; CAP-18; hCAP-18Cleaved into the following 2 chains:Antibacterial protein FALL-39; Alternative name(s):; FALL-39 peptide antibiotic
products gene name :
cAMP
other gene names :
CAMP; CAMP; LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39; CAP18; FALL39
uniprot entry name :
CAMP_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
This antibody recognizes camp, not cross react with 5/- AMP, 5’-ADP, 5’-ATP or 3’, 5’-cGMP.
purity :
The mouse monoclonal antibody is purified by protein A Affinity Purification.
form :
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
concentration :
Size: 100 ug/200 ul
storage stability :
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. Avoid repeated freezing-thawing cycles.
tested application :
ELISA, Western Blot
app notes :
Western Blot: 0.1-1 ug/ml. ELISA: 0.01-0.1 ug/ml
other info1 :
Antigen Preparation: A chemically linked 3', 5'-Cyclic Adenosine Monophosphate (cAMP)
other info2 :
Positive Control: cAMP-Carrier protein
products description :
Cyclic adenosine monophosphate (cAMP) is an intracellular mediator that plays an important role in a variety of hormone signaling. It's been known as an universal cytoplasmic second messenger in drug discovery due to the involvement of G-Protein Coupled Receptors (GPCR) signaling events where the receptors are activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, etc.
products references :
Chika Funaki, et al, Role of cAMP inhibition of p44/p42 mitogen-activated protein kinase in potentiation of protein secretion in rat lacrimal gland. Am J Physiol Cell Physiol 293: C1551-C1560, 2007.
ncbi acc num :
CAG46759.1
ncbi gb acc num :
CR541961.1
ncbi mol weight :
19,301 Da
ncbi pathways :
Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352); Tuberculosis Pathway (213780); Tuberculosis Pathway (213743)
ncbi summary :
Cathelicidin antimicrobial protein is an antimicrobial protein found in specific granules of polymorphonuclear leukocytes (PMNs).[supplied by OMIM]
uniprot summary :
Function: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Ref.11 Ref.12. Subcellular location: Secreted. Tissue specificity: Expressed in bone marrow and testis and neutrophils. Post-translational modification: The N-terminus is blocked. Sequence similarities: Belongs to the cathelicidin family. Caution: Ref.8 sequence was incorrectly assigned to originate from M.mulatta.