This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Hepcidin (Hepc) ELISA Kit
catalog :
MBS454800
quantity :
48-Strip-Wells
price :
385 USD
product information
catalog number :
MBS454800
products type :
ELISA Kit
products full name :
Human Hepcidin (Hepc) ELISA Kit
products short name :
[Hepcidin (Hepc)]
products name syn :
[HAMP; HFE2B; PLTR; LEAP1; Hepcidin Antimicrobial Peptide; Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor]
other names :
[hepcidin preproprotein; Hepcidin; hepcidin; hepcidin antimicrobial peptide; Liver-expressed antimicrobial peptide 1; LEAP-1]
products gene name :
[Hepc]
other gene names :
[HAMP; HAMP; HEPC; PLTR; HFE2B; LEAP1; HEPC; LEAP1; LEAP-1; PLTR; Hepc25; Hepc20]
reactivity :
Human
sequence length :
84
storage stability :
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. Assay Type: Sandwich. Detection Range: 62.5-4000pg/mL. Sensitivity: 23.5pg/mL
other info2 :
Intra Assay: CV<10%. Inter Assay: CV<12%
ncbi gi num :
10863973
ncbi acc num :
NP_066998.1
ncbi gb acc num :
NM_021175.3
uniprot acc num :
P81172
ncbi mol weight :
9,408 Da
ncbi pathways :
Hfe Effect On Hepcidin Production Pathway (1471250); Iron Metabolism In Placenta Pathway (672461)
ncbi summary :
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Oct 2014]
uniprot summary :
Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes (PubMed:22306005).
size1 :
48-Strip-Wells
price1 :
385 USD
size2 :
96-Strip-Wells
price2 :
515
size3 :
5x96-Strip-Wells
price3 :
2325
size4 :
10x96-Strip-Wells
price4 :
4515
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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