catalog number :
MBS454552
products type :
ELISA Kit
products full name :
Human Semaphorin 3A (SEMA3A) ELISA Kit
products short name :
[Semaphorin 3A (SEMA3A)]
other names :
[semaphorin-3A; Semaphorin-3A; semaphorin-3A; semaphorin 3A; Semaphorin III; Sema III]
products gene name :
[SEMA3A]
other gene names :
[SEMA3A; SEMA3A; HH16; SemD; COLL1; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III; SEMAD; Sema III]
storage stability :
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
other info1 :
Samples: Serum, plasma, tissue homogenates and other biological fluids. Assay Type: Sandwich. Detection Range: 1.56-100ng/mL. Sensitivity: 0.57ng/mL
other info2 :
Intra Assay: CV<10%. Inter Assay: CV<12%
ncbi acc num :
NP_006071.1
ncbi gb acc num :
NM_006080.2
ncbi mol weight :
88,889 Da
ncbi pathways :
Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (1270303); CRMPs In Sema3A Signaling Pathway (1270310); Developmental Biology Pathway (1270302); SEMA3A-Plexin Repulsion Signaling By Inhibiting Integrin Adhesion Pathway (1270308); Sema3A PAK Dependent Axon Repulsion Pathway (1270309); Semaphorin Interactions Pathway (1270304)
ncbi summary :
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq, Jul 2008]
uniprot summary :
Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1.
size4 :
10x96-Strip-Wells