catalog number :
MBS452241
products type :
ELISA Kit
products full name :
Human Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B) ELISA Kit
products short name :
[Fc Fragment Of IgG Low Affinity IIIb Receptor (FcgR3B)]
products name syn :
[CD16B,FCG3,Fc-gamma RIII,Fc-gamma RIIIb,Fc-gamma RIII-beta,FCGR3,FcR-10,FcRIII,FcRIIIb,IGFR3,IgG Fc receptor III-1,Low affinity immunoglobulin gamma Fc region receptor]
other names :
[low affinity immunoglobulin gamma Fc region receptor III-B isoform 2; Low affinity immunoglobulin gamma Fc region receptor III-B; low affinity immunoglobulin gamma Fc region receptor III-B; Fc fragment of IgG receptor IIIb; Fc-gamma RIII-beta; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb; FcR-10; IgG Fc receptor III-1; CD_antigen: CD16b]
products gene name :
[FcgR3B]
other gene names :
[FCGR3B; FCGR3B; CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb; CD16B; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb]
storage stability :
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
other info1 :
Samples: Serum, plasma, tissue homogenates, cell lysates and other biological fluids. Assay Type: Sandwich. Detection Range: 1.25-80ng/mL. Sensitivity: 0.55ng/mL
other info2 :
Intra Assay: CV<10%. Inter Assay: CV<12%
ncbi acc num :
NP_000561.3
ncbi gb acc num :
NM_000570.4
ncbi mol weight :
26,216 Da
ncbi pathways :
Immune System Pathway (1269170); Innate Immune System Pathway (1269203); Leishmaniasis Pathway (144181); Leishmaniasis Pathway (144028); Metabolism Of Proteins Pathway (1268677); Natural Killer Cell Mediated Cytotoxicity Pathway (83079); Natural Killer Cell Mediated Cytotoxicity Pathway (490); Neutrophil Degranulation Pathway (1457780); Osteoclast Differentiation Pathway (193147); Osteoclast Differentiation Pathway (193096)
ncbi summary :
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]
uniprot summary :
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
size4 :
10x96-Strip-Wells