catalog number :
MBS451733
products type :
ELISA Kit
products full name :
Human Occludin (OCLN) ELISA Kit
products short name :
[Occludin (OCLN)]
products name syn :
[Tight Junction Protein Occludin TM4 Minus]
other names :
[occludin isoform a; Occludin; occludin; occludin]
products gene name :
[OCLN]
other gene names :
[OCLN; OCLN; BLCPMG; PPP1R115]
storage stability :
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
image1 heading :
Typical Standard Curve/Testing Data
other info1 :
Samples: Tissue homogenates, cell lysates and other biological fluids. Assay Type: Sandwich. Detection Range: 0.156-10ng/mL. Sensitivity: 0.058ng/mL
other info2 :
Intra Assay: CV<10%. Inter Assay: CV<12%
ncbi acc num :
NP_001192183.1
ncbi gb acc num :
NM_001205254.1
ncbi mol weight :
8,175 Da
ncbi pathways :
Apoptosis Pathway (1270262); Apoptotic Cleavage Of Cell Adhesion Proteins Pathway (1270290); Apoptotic Cleavage Of Cellular Proteins Pathway (1270288); Apoptotic Execution Phase Pathway (1270287); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Leukocyte Transendothelial Migration Pathway (83083); Leukocyte Transendothelial Migration Pathway (494)
ncbi summary :
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
uniprot summary :
May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions.
size4 :
10x96-Strip-Wells