catalog number :
MBS450867
products type :
ELISA Kit
products full name :
Mouse Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61) ELISA Kit
products short name :
[Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61)]
products name syn :
[CCN1; GIG1; IGFBP10; CCN family member 1; Insulin-like growth factor-binding protein 10]
other names :
[protein CYR61; Protein CYR61; protein CYR61; cysteine rich protein 61; 3CH61; CCN family member 1; Cysteine-rich angiogenic inducer 61; Insulin-like growth factor-binding protein 10; IBP-10; IGF-binding protein 10; IGFBP-10]
products gene name :
[CYR61]
other gene names :
[Cyr61; Cyr61; CCN1; Igfbp10; AI325051; Ccn1; Igfbp10; IBP-10; IGF-binding protein 10; IGFBP-10]
storage stability :
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, plasma, tissue homogenates and other biological fluids. Assay Type: Sandwich. Detection Range: 15.625-1000pg/mL. Sensitivity: 5.4pg/mL
other info2 :
Intra Assay: CV<10%. Inter Assay: CV<12%
ncbi acc num :
NP_034646.1
ncbi gb acc num :
NM_010516.2
ncbi mol weight :
41,709 Da
ncbi pathways :
Hypertrophy Model Pathway (198326); PodNet: Protein-protein Interactions In The Podocyte Pathway (755428); XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway (755427)
uniprot summary :
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (). CYR61-mediated gene regulation is dependent on heparin-binding (). Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (). Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3 ().
size4 :
10x96-Strip-Wells