catalog number :
MBS450267
products type :
ELISA Kit
products full name :
Human Eosinophil Peroxidase (EPX) ELISA Kit
products short name :
[Eosinophil Peroxidase (EPX)]
products name syn :
[EPO; EPP; EPX-PEN; EPER]
other names :
[eosinophil peroxidase preproprotein; Eosinophil peroxidase; eosinophil peroxidase; eosinophil peroxidase]
products gene name :
[EPX]
other gene names :
[EPX; EPX; EPO; EPP; EPXD; EPX-PEN; EPER; EPO; EPP; EPO]
storage stability :
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
image1 heading :
Typical Testing Data/Standard Curve (for reference only)
other info1 :
Samples: Serum, plasma, tissue homogenates and other biological fluids. Assay Type: Sandwich. Detection Range: 1.25-80ng/mL. Sensitivity: 0.51ng/mL
other info2 :
Intra Assay: CV<10%. Inter Assay: CV<12%
ncbi acc num :
NP_000493.1
ncbi gb acc num :
NM_000502.5
ncbi mol weight :
81,040 Da
ncbi pathways :
Asthma Pathway (83120); Asthma Pathway (532); Immune System Pathway (1269170); Innate Immune System Pathway (1269203); Neutrophil Degranulation Pathway (1457780)
ncbi summary :
This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. [provided by RefSeq, Feb 2016]
uniprot summary :
Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.
size4 :
10x96-Strip-Wells