catalog number :
MBS448043
products full name :
Rab8 Pan Polyclonal Antibody
products short name :
Rab8
products name syn :
Anti-Rab8
other names :
Rab8, isoform C; LD44762p; CG8287 gene product from transcript CG8287-RA; CG8287-PA; CG8287-PB; CG8287-PC; Rab-protein 8; Rab8; Rab8-PA; Rab8-PB; Rab8-PC; l(3)76BDu
products gene name :
Rab8
other gene names :
Rab8; Rab8; AAF49101; CG8287; Dm Rab8; dm-Rab8; DmelCG8287; DmRab8; DRab8; DRAB8; l(3)76BDu; Rab-r8; rab8; rab8
uniprot entry name :
O18338_DROME
reactivity :
Reacts against human, rat, mouse, canine and monkey proteins.
specificity :
Detects total Rab8 protein in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab8a and GFPRab8b cds by Western blot.
form :
Polyclonal antibody supplied as a 200 uL (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
storage stability :
Store at -20 degree C for long-term storage. Store at 2-8 degree C for up to one month.
tested application :
Immunofluorescence (IF), Western Blot (WB)
app notes :
Western blot: 1:250-1: 1,000. Immunofluorescence: 1:50-1:250. Immunohistochemistry (paraffin): 1:250-1: 1,500. Immunohistochemistry (frozen): 1:250-1: 1,500
other info1 :
Gene Identifier: ENSG00000167461. Immunogen: Purified recombinant peptide derived from within residues 170 aa to the C-terminus of mouse Rab8a produced in E. coli. Antigen: Purified recombinant peptide derived from within residues 170 aa to the C-terminus of mouse Rab8a and Rab8b produced in E. coli.
products description :
Goat polyclonal antibody to mouse Rab8. Rab8 belongs to the small GTPase superfamily, Rab family. It has cell-type specific function during the process of exocytosis and coordinates regulation of the cytoskeleton. Rab8 also appears to interface with endocytic recycling circuits. At the molecular level, this GTPase regulates both the export of vesicles from the transGolgi apparatus, and the directed translocation along actin filaments and microtubules.
ncbi acc num :
NP_001246837.1
ncbi gb acc num :
NM_001259908.2
ncbi mol weight :
23,691 Da
ncbi pathways :
Cell Cycle Pathway (931417); Cell Cycle, Mitotic Pathway (931433); G2/M Transition Pathway (931450); Membrane Trafficking Pathway (931724); Mitotic G2-G2/M Phases Pathway (931448); Regulation Of PLK1 Activity At G2/M Transition Pathway (931453); Translocation Of GLUT4 To The Plasma Membrane Pathway (931734)
uniprot summary :
Sequence similarities: Belongs to the small GTPase superfamily. Rab family. RuleBase RU003315